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 The current interest of my lab is molecular signaling of innate immunity mediated by Nod proteins. I am looking for a motivated candidate to join my lab and study the functions of signaling molecules in the immune system. This research project includes functional analysis of genetically altered mice in disease models and in vitro assays. The candidate should have a PhD or MD with experience in molecular or cellular immunology documented by a strong publication record. Information for the scientific topics of our field is available in our recent review in Inohara & Nunez (2003) Nature Review of Immunology 3, 371-382. More information for our publications is also available at

Naohiro Inohara

Department of Pathology,
University of Michigan
Contact information:

Caspases / other proteases Transcription factors, Translation factors
Caspase regulators / NODs TNF & TNFR families
Bcl-2 family IL & ILR families
Death domain proteins Toll, Ig, selectin, chemokine families
Protein kinases/phosphatases Other NF-kB regulators
Viral apoptosis inhibitors Engulfment (under construction)
Lipid enzymes and its regulators RING, E2 & E3-related
Other apoptosis regulators Apoptosis regulators in zebrafish
More factors Alphabetical Index
How to use this site Go to other immunology sites in the link table of Nat. Immunol.

Online References
by Baehrecke (Nat Rev Mol Cell Biol 2002), Jacobson et al. (Cell 1998), Peter et al. (Proc. Natl. Acad. Sci. 1997)
Apoptosis Regulators by Strasser et al. (Annu Rev Biochem 1999), Strasser et al., (Annu Rev Biochem 2000)

[Special Topics]
Apoptosis by Bacterial Pathogens, reviewed by Weinrauch & Zychlinsky (Annu Rev Microbiol  1999)
Cell Cycle... by King & Cidlowski (Annu. Rev. Physiol. 1998)
Cellular responses to DNA Damage by Norbury  & Hickson (Annu Rev Pharmacol Toxicol 2001)
Glucocorticoids in T cell development and function by Ashwell et al. (Annu Rev Immunol 2000) James  (Annu. Rev. Physiol. 1998)
Immune systems by Rathmell & Thompson (Annu. Rev. Immunol. 1999), Lenardo et al. (Annu. Rev. Immunol. 1999)
Interferon-g... by Boehm et al. (Annu. Rev. Immunol. 1997)
Kidney Development  by Pohl et al. (Annu Rev Physiol 2000)
Mitochondira... by Kroemer et al. (Annu. Rev. Physiol. 1998)
Myc... by E. Brad Thompson (Annu. Rev. Physiol. 1998)
Neural Development and Disease by Nijhawan et al. (Annu. Rev. Neurosci. 2000)
Neuronal Survival and Regeneration by Goldberg & Barres (Annu Rev Neurosci  2000)
Ovary.. by Kaipia & Hsueh (Annu. Rev. Physiol. 1998)
Plant PCD & pathogen responses, review by Gilchrist (Annu. Rev. Immunol. 1998), Joosten & deWit, Hutcheson, Dow et al. (Annu. Rev. Phytopathol. 1999)

Nunez, G., Benedict, M.A., Hu, Y., Inohara, N. "Caspases: The proteases of the apoptotic pathway." Oncogene 1998 Dec 24;17(25):3237-45  <<<direct download the PDF file from the publisher's site>>>

Apoptosis Scientists on Web.

On-line Review of Apoptosis (Japanese)

Copyright by Naohiro Inohara, Department of Pathology, University of of Michigan Medical School
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