Regulators of Engulfment & Endocytosis (under construction)
 

Group	Name	Apoptosis	KO	Structure	binding partner	locus
Ced-1	SREC, SCARF1(human), Ced-1(C.e.),	enhance		EGF x8		17p13.3
Ced-2	Ced-2(C.e.), Crk-II(human)	enhance		SH2/SH3x2		17p13.3
Ced-5	Ced-5(C.e.),  myoblast city (D.m.), dock180(human),	enhance
Ced-5 related	KIAA0299, AC003077, AC003080 (human) ,DocA(D.d.), YLR422w(S.c.), trg(rat)
Ced-6	Ced-6(C.e.), GULP (human)	enhance		PTB	CD91, CED-1
Ced-7	Ced-7(C.e.)	enhance		ABC
Ced-10	Ced-10(C.e.),  Rac(human) For more small G, see here	enhance		G
Ced-12
scr	CD36(human), Croquemort (fly), C.e.(scr-1,2,3,4,5,6)		L				PPARg
	CD163 (human, mouse)			SRx9		12p13.3	GM-CSF
	M160 (human)			SRx12/TM		12p13.31
Mer	Mer
PS R	phosphatidylserine receptor (human, mouse)					17q25

Links
Caenorhabditis elegans WWW Server

On-line Review

Corralling the Corpses by Hengartner (Cell 2001)

Copyright by Naohiro Inohara, Department of Pathology, University of of Michigan Medical School