Copyright by Naohiro
Inohara, Department of Pathology, University of of Michigan
Medical School| Index | Caspase | CARD/DED/BIR | Bcl-2 | DD | TNF/TNFR | Kinases | ILs | Viral | Lipid | Engulf | TF | RING | Toll | Other Apop | Other NFkB | Alphabet |
Viral Apoptotic Inhibitors
| Function as | Viral protein (virus) | |
| Competitor of death receptor | crmB(Poxvirus),G4R(VMV),B28R(VV),T2(MV,RFV),C5L(cPV),A53(VcV) etc | TNFR homologue |
| DED | E8(EHV2),M159L/M160L(MCV1), K13(KSAV/hHV8),E1.1(BHV4), VG71(HVS11),Q2/2L(CPV) etc | FLIPs |
| Bcl-2 like protector | BHRF1(SCV),LMW5-HL(ASFV),ORF16(HVS11),vBcl-2(KSAV/hHV8),E1B 19K(Adenovirus) | |
| IAPs | baculoviral IAPs(list) | |
| caspase inhibitor | crmA(cPV),p35(BMNPV, AcNV, SLNPV, HANV), p49 (,SLNPV), UL36/vICA(CMV5,HHV7,) | 3D(p35, w/casp8) |
| bona fide IkB | A238L(ASFV) | RelA, Calcineurin |
| TIR inhibitor(?) | A46R(VACCV)/A52R(VARV) | no homo to TIR |
| CARD | E10/vCARMEN/vCLAP(EHV2) | |
| CIDE inhibitor | NS2(HCV) | |
| Other | E4ORF4 (CAdV1, CAdV2) | |
| UL37(CMV), |
Online references
Review: Virus and Apoptosis by Roulston, Marcellus & Branton (Annu. Rev. Microbiol. 1999), by Griffin & Hardwick (Annu. Rev. Microbiol. 1997)
Copyright by Naohiro
Inohara, Department of Pathology, University of of Michigan
Medical School| HOME | All-in-One Seq Analyzer |