Chronis Lab

Address:

2178 GG Brown
Department of Mechanical Engineering
2350 Hayward Street
University of Michigan
Ann Arbor, MI 48109

phone (office): 734-936-0343

Biography

Education
B.A. University of Crete, Greece
Biology, 2002
M.Sc.University of Crete, Greece
Molecular Biology and Biotechnology, 11/2004
Ph.D. University of Crete, Greece
Molecular Biology and Biotechnology, 03/2009
‘’Characterization of PQN-21, A Prion-like Protein Involved in Learning and Memory in
C. elegans’’

Research training
2000-2002. University of Crete, Greece, Department of Biology
Senior Thesis research
Laboratory of Human Molecular Genetics: Structural and functional analysis of the Neurl gene in mice.
2002-2004. Institute of Molecular Biology and Biotechnology, Crete, Greece
Predoctoral research
a) Laboratory of Protein Biochemistry and Crystallography. Purification of ChiA and BSA proteins.
b) Laboratory of Yeast Molecular Genetics. Study of chromosomal interactions of transcription factors in Saccharomyces cerevisiae by ChIP.
c) Laboratory of Nematode Molecular Genetics. RNAi silencing of the ncx genes in C. elegans. Functional studies of DEG/ENaC ion channels in C. elegans. Phenotypic and functional analysis of pqn-21 in C. elegans.

Doctoral Thesis research
Summer 2006. Centre d'Immunologie de Marseille-Luminy, Université de la Méditerranée, France
Jonathan Ewbank Lab. Induction of necrosis during bacterial infection in C. elegans.

Doctoral Thesis research
2005-2009. Institute of Molecular Biology and Biotechnology, Crete, Greece
Laboratory of Nematode Molecular Genetics. Phenotypic and functional analysis of pqn-21 in C. elegans. Tools for mutagenesis and transgenesis in C. elegans, based on the Minos transposon.

Teaching experience
2002-2003. High School Biology Instructor. Heraklion, Greece.
2003-2004. University of Crete, Greece Department of Biology. Graduate Teaching Instructor.
2004-2009. Institute of Molecular Biology and Biotechnology, Crete, Greece. Bench Supervisor.

Distinctions and Awards
2002-2003. Institute of Molecular Biology and Biotechnology, Crete, Greece
One year fellowship for Graduate Studies.
2003-2004. National Fellowship Foundation of Greece
One year fellowship for Graduate Studies.


Publications

• Bazopoulou M. D., Troulinaki K. and Tavernarakis N. (2004). Protein Turnover and ageing. In Focus on Protein Research, (Frank Columbus and John W. Robinson, editors) Nova Science Publishers, Inc. New York.
• Bazopoulou M. D., Voglis G. and Tavernarakis N. (2005). The role of DEG/ENaC ion channels in sensory mechanotransduction. In Molecular Sensors for Cardiovascular Homeostasis. (Donna Wang, editor) Springer Science Academic Publishers, New York.
• Bazopoulou D. and Tavernarakis N. (2007). Mechanosensitive Ion Channels in Caenorhabditis elegans. In Current Topics in Membranes: Mechanosensitive Ion Channels, (Owen Hamill, Sidney Simon and Dale Benos, editors), Elsevier Inc., Academic Press, San Diego, USA.
• Wong D., Bazopoulou D., Pujol N., Tavernarakis N. and Ewbank J. J. (2007). Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection. In Genome Biology, 8: R194. http://www.ncbi.nlm.nih.gov/pubmed/17875205
• Bazopoulou D. and Tavernarakis N. (2009). The NemaGENETAG initiative: large scale transposon insertion gene-tagging in Caenorhabditis elegans, In Genetica, 137(1):39-46.
• Chokshi T.V., Bazopoulou D., Chronis N. (2010). An automated microfluidic platform for calcium imaging of chemosensory neurons in Caenorhabditis elegans. In Lab on a Chip, 10(20):2758-63.