S. Liu*, S.H. Patel, C. Ginestier, I. Ibarra, R. Martin-Trevino, S. Bai, S. McDermott, L. Shang, J. Ke, S.J. Ou, A. Heath, K.J. Zhang, H. Korkaya, S.G. Clouthier, E. Charafe-Jauffret, D. Birnbaum, G.J. Hannon, and M.S. Wicha. MicroRNA93 Modulates Breast Cancer Stem Cells by Regulating their Proliferation and Differentiation (accepted by PlosGenetics, *Corresponding Author).

S. Liu, H Korkaya, M.S. Wicha. Are cancer stem cells ready for prime time? The Scientist. April 1, 2012.

S. Liu, S.G. Clouthier, M.S. Wicha. Role of microRNAs in the regulation of breast cancer stem cells. Journal of mammary gland biology and neoplasia February 14 (online), 2012.

S. Liu*, C. Ginestier, S.J. Ou, S.G. Clouthier, S.H. Shivani, F. Monville, H. Korkaya, A. Heath, J. Dutcher, C. Kleer, Y. Jung, G. Dontu, R. Taichman, M.S. Wicha*. Mesenchymal stem cells regulate breast cancer stem cells defining a cancer stem cell niche. Cancer Res 71(2); 614-24, 2011. (Cover featured, *Corresponding Author). PMID: 21224357

H. Korkaya, S. Liu, M.S. Wicha. Breast cancer stem cells, cytokine networks, and the tumor microenvironment. Journal of Clinical Investigation. 2011 Oct 3;121(10):3804-9. PMID: 21965337

I. Kryczek, S. Liu, M. Roh, L. Vatan, W. Szeliga, S. Wei, M. Banerjee, Y. Mao, J. Kotarski, M.S. Wicha, R. Liu, and W. Zou. Expression of aldehyde dehydrogenase and CD133 defines ovarian cancer stem cells. International Journal of Cancer. 2011. PMID: 21480217

J. Wu, S. Liu, G. Liu, A. Dombkowski, J. Abrams, R. Martin-Trevino, M.S. Wicha, S.P. Ethier, Z.Q. Yang. Identification and functional analysis of 9p24 amplified genes in human breast cancer. Oncogene. 31(3):333-41, 2012. PMID: 21666724

Regulation of Cancer Stem Cells by Cytokine Networks: Attacking Cancers Inflammatory Roots.H. Korkaya, S. Liu, M.S. Wicha*. Clin Cancer Res. 17(19): 6125-6129, 2011. PMID: 21685479.

S. Liu, M. S. Wicha. Targeting breast cancer stem cells. Journal of Clinical Oncology 28(25): 4006-4012, 2010. PMID: 20498387

Y. Li, T. Zhang, H. Korkaya, S. Liu, H.F. Lee, B. Newman, Y. Yu, S.G. Clouthier, S.J. Schwartz, M.S. Wicha, and D. Sun. Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells. Clinical Cancer Research 16(9):2580-90, 2010. PMID: 20388854

S.T. Shu, Y. Sugimoto, S. Liu, H.L. Chang, W. Ye, L.S. Wang, Y.W. Huang, P. Yan, Y.C. Lin. Function and regulatory mechanisms of the candidate tumor suppressor receptor protein tyrosine phosphatase gamma (PTPRG) in breast cancer cells. Anticancer Res. 30(6):1937-46, 2010. PMID: 20651337.

C. Ginestier, S. Liu, M.E. Diebel, H. Korkaya, M. Luo, J. Dutcher, M. Brown, E. Charafe-Jauffret, D. Birnbaum, J.L. Guan, G. Dontu, M.S. Wicha. CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts. JCI 120(2):485-97. PMID: 20051626

C. Ginestier, S. Liu, M.S. Wicha. Getting to the root of BRCA1-deficient breast cancer. Cell Stem Cell 5 (3): 229-230, 2009. PMID: 19733528

G Deniz, S. Liu, M.S. Wicha, A. Shukla, D Krag. Identification of Single Chain Antibodies to Breast Cancer Stem Cells Using Phage Display. Biotechnology progress 25(6):1780-7, 2009. PMID: 19899107

M. Luo, H. Fan, T. Nagy, H. Wei, C. Wang, S. Liu, M.S. Wicha, J.L. Guan. Mammary Epithelial-Specific Ablation of the Focal Adhesion Kinase Suppresses Mammary Tumorigenesis by Affecting Mammary Cancer Stem/Progenitor Cells. Cancer Research 62 (2): 466-474, 2009. PMID: 19147559

M. Kakarala, D.E. Brenner, H. Korkaya, C. Cheng, K. Tazi, C. Ginestier, S. Liu, G. Dontu, M.S. Wicha. Targeting breast stem cells with the cancer preventive compounds curcumin and piperine. Breast Cancer Res Treat. 2009. PMID: 19898931

H.L. Chang, Y. Sugimoto, S. Liu, L.S. Wang, Y.W. Huang, W. Ye, Y.C. Lin. Keratinocyte growth factor (KGF) regulates estrogen receptor-alpha (ER-alpha) expression and cell apoptosis via phosphatidylinositol 3-kinase (PI3K)/Akt pathway in human breast cancer cells. Anticancer Res. 29(8):3195-205, 2009.

S. Liu, C. Ginestier, E. Charafe-Jauffret, H. Foco, C.G. Kleer, S.D. Merajver, G. Dontu, M.S. Wicha. BRCA1 Regulates Human Mammary Stem/Progenitor Cell Fate. PNAS (USA) 105 (5): 1680-1685, 2008. PMID: 18230721

L.S. Wang, Y.W. Huang, S. Liu, P. Yan, Y.C. Lin. Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue. BMC cancer 8: 208-221, 2008. PMID: 18652667

C. Ginestier, M.H. Hur, E. Charafe-Jauffret, F. Monville, J. Dutcher, M. Brown, J. Jacquemier, P. Viens, C.G. Kleer, S. Liu, A. Schott, D. Hayes, D. Birnbaum, M.S. Wicha, D. Dontu. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1: 555-567, 2007. PMID: 18371393

M.S. Updike, J.C. Sawdy, L.S. Wang, S. Liu, Y.W. Huang, W. Ye, W.B. Farrar, Y.C. Lin, M. Wick. Primary cultured human breast epithelial cells up-regulate protein disulfide isomerase in response to zeranol. Anticancer Res. 27(1A):407-10, 2007.

S. Liu, G. Dontu, I. Mantle, S. Patel, N. Ahn, K.W. Jackson, P. Suri, and M.S. Wicha. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Research 66: 6063-6071, 2006. PMID: 16778178

M.S. Wicha, S. Liu, and G. Dontu. Cancer Stem Cells: An Old Idea--A Paradigm Shift. Cancer Research 66(4): 1883-1890, 2006. PMID: 16488983

H.L. Chang, Y. Sugimoto, S. Liu, W. Ye, L.S. Wang, Y.W. Huang, Y.C. Lin. Keratinocyte growth factor (KGF) induces tamoxifen (Tam) resistance in human breast cancer MCF-7 cells. Anticancer Res. 26(3A):1773-84, 2006.

L.S. Wang, Y.W. Huang, S. Liu, H.L. Chang, W. Ye, S. Shu, Y. Sugimoto, J.A. Funk, D.D. Smeaks, L.N. Hill, Y.C. Lin. Conjugated linoleic acid (CLA) modulates prostaglandin E2 (PGE2) signaling in canine mammary cells. Anticancer Res. 26(2A):889-98, 2006.

L.S. Wang, Y.W. Huang, Y. Sugimoto, S. Liu, H.L. Chang, W. Ye, S. Shu, and Y.C. Lin. Conjugated linoleic acid (CLA) up-regulates the estrogen-regulated cancer suppressor gene, protein tyrosine phosphatase gamma (PTPgama), in human breast cells. Anticancer research 26(1A): 27-34, 2006.

S. Liu, G. Dontu, and M.S. Wicha. Mammary stem cells, self-renewal pathways, and carcinogenesis. Breast cancer research 7(3): 86-95, 2005. PMID: 15987436

G. Dontu, S. Liu, and M.S. Wicha. Stem Cells in Mammary Development and Carcinogenesis: Implications for Prevention and Treatment. Stem cell reviews 1(3): 207-214, 2005. PMID: 17142857

I. Mantle, G. Dontu, S. Liu, and M.S. Wicha. Cancer stem cells: implications for development of more effective therapies. Cancer drug resistance, PART II: Biological Resistance. 2005.

L.S. Wang, Y.W. Huang, Y. Sugimoto, S. Liu, H.L. Chang, W. Ye, S. Shu, and Y.C. Lin. Effects of human breast stromal cells on conjugated linoleic acid (CLA) modulated vascular endothelial growth factor-A (VEGF-A) expression in MCF-7 cells. Anticancer research 25(6B): 4061-8, 2005.

J. Jiang, Y. Sugimoto, S.K. Kulp, S. Liu, H.L. Chang, K.Y. Park, and Y.C. Lin. Inhibitory effects of gossypol on human prostate cancer cells-PC3 are associated with transforming growth factor signal transduction pathway. Anticancer research 24(1): 91-100, 2004.

S. Liu, and Y.C. Lin. Transformation of Human Breast Epithelial Cells MCF-10A by Environmental Disruptor, Zeranol (Z), and estradiol-17 (E2). The breast journal 10 (6): 514-521, 2004.

S. Liu, Y. Sugimoto, C. Sorio, P. Melotti, and Y.C. Lin. Functional analysis of estrogenically regulated Protein Tyrosine phosphatase-(PTP) in vitro in human breast cancer. Oncogene 23: 1256-1262, 2004.

S. Liu, Y. Sugimoto, S.K. Kulp, J. Jiang, H. Chang, K.Y. Park, Y. Kashida, and Y.C. Lin. Estrogenic down-regulation of Protein Tyrosine Phosphatase (PTP) in human breast is associated with Estrogen Receptor Anticancer Research 22: 3917-3924, 2002.

S. Liu, S.K. Kulp, Y. Sugimoto, J. Jiang, H. Chang, and Y.C. Lin. Involvement of Breast Epithelial stromal Interactions in the Regulation of Protein Tyrosine phosphatase-(PTP) mRNA Expression by Estrogenically Active Agents. Breast Cancer Research and Treatment 71: 21-35, 2002.

S. Liu, S.K. Kulp, Y. Sugimoto, J. Jiang, H. Chang, and Y.C. Lin. The (-)-enantiomer of gossypol possesses higher anticancer potency than racemic gossypol in human breast cancer. Anticancer Research 22: 33-38, 2002.

J. Jiang, P.K. Gosh, S.K. Kulp, Y. Sugimoto, S. Liu, J. Czekajewski, H.L. Chang, and Y.C. Lin. Effects of gossypol an O2 consumption and CO2 production in human prostate cancer cells. Anticancer research 22: 1491-1496, 2002.

J. Jiang, S.K. Kulp, Y. Sugimoto, S. Liu, and Y.C. Lin. The effects of Gossypol on the invasiveness of MAT-Lylu Cells and MAT-Lylu Cells from the metastasized longs of MAT-Lylu-bearing copenhagen rats. Anticancer research 20: 4591-4598, 2000.

D. Ruan, J. Chen, W. Zhao, S. Liu, W. Gu. Effects of Lead on L-LTP and PPF in Hippocampal Dentate Gyrus. Guangdong Weiliang Yuansu Kexue 5: 25-29, 1998.