|YANG RESEARCH GROUP MEMBERS - Lindsay White|
Phone: (734) 647-9708
Biochemistry, University of Northern Colorado, 2006
The treatment of cancer is often hindered by the lack of therapeutic specificity toward the tumor tissue which results in drug toxicity.  The goal of my project is to investigate a systemically administered antibody targeted siRNA delivery system. This delivery system is composed of three components that will combine antibody targeting, prodrug type activation, and a tumor specific siRNA as the drug.  The system will be targeted with a tumor specific antibody to enable accumulation at the tumor site or even metastatic sites.  The prodrug feature is necessary to promote siRNA entry into the cell.  Once the siRNA enters the cell it will knock down a specific mRNA.
American Foundation for Pharmaceutical Education Pre-Doctoral Fellowship
Lindsay grew up in rural eastern Colorado and attended undergrad in Colorado before moving to Ann Arbor for graduate school. When not pursuing pharmaceutics, she enjoys spending time with family and friends, listening to music, playing cards, and reading. Because she loves skiing the beautiful Rocky Mountains of Colorado, she hopes to one day own a cabin there to enjoy during vacations.