2005

Zhu, X.; Mills, K. L.; Peters, P. R.; Bahng, J. H.; Liu E. H.; Shim, J.; Naruse, K.; Csete, M. E.; Thouless, M. D.; Takayama, S. “Fabrication of Reconfigurable Protein Matrices by Cracking” Nat. Mater. 2005, 4, 403-406.

Song, J. W.; Gu, W.; Futai, N.; Warner, K. A.; Nor, J. E.; Takayama, S. “Computer-Controlled Microcirculatory System for Endothelial Cell Culture and Shearing” Anal. Chem. 2005, 77, 3993-3999.

Huh, D.; Kamotani, Y.; Grotberg, J. B.; Takayama, S. “Microfluidics for Flow Cytometric Analysis of Cells and Particles” Physiol. Meas. 2005, R73-R98.

2004

Gu, W.; Zhu, X.; Futai, N.; Cho, B. S.; Takayama, S. “Computerized Microfluidic Cell Culture Using Elastomeric Channels and Braille Displays” Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 15861-15866.

Futai, N.; Gu, W.; Takayama, S. “Rapid Prototyping of Microstructures with Bell-Shaped Cross-Sections and Its Application to Deformation-Based Microfluidic Valves” Adv. Mater. 2004, 16, 1320-1323.

Zhu, X.; Chu, L. Y.; Chueh, B.-H.; Shen, M.; Hazarika, B.; Phadke, N.; Takayama, S. ”Arrays of Horizontally-Oriented Mini-Reservoirs Generate Steady Microfluidic Flows for Continuous Perfusion Cell Culture and Gradient Generation” Analyst 2004, 1026-1031.

Zhu, X.; Bersano-Begey, T. F.; Takayama, S. “Nanomaterials for Cell Engineering” Encyclopedia of Nanoscience and Nanotechnology, Ed. Nalwa, H. S., 2004, 6, 857-878.

2003

Takayama, S.; Ostuni, E.; LeDuc, P. Naruse, K.; Ingber, D. E.; Whitesides, G. M. “Selective Chemical Treatment of Cellular Microdomains Using Multiple Laminar Streams” Chem. Biol., 2003, 10, 123-130.

Shim, J.; Bersano-Begey, T. F.; Zhu, X.; Tkaczyk, A.; Linderman, J.J.; Takayama, S. “Micro- and Nanotechnologies for Studying Cellular Function” Curr. Top. Med. Chem., 2003, 3, 687-703.

Cho, B.; Schuster, T.G.; Zhu, X.; Chang, D.; Smith, G.D.; Takayama, S. “A Passively-Driven Integrated Microfluidic System for Separation of Motile Sperm” Anal. Chem. 2003, 75, 1671-1675.

Schuster, T.G.; Cho, B.; Keller, L. M.; Takayama, S.; Smith, G. D. “Isolation of Motile Sperm From Semen Samples Using MicrofluidicsReproduc. Biomed. Online. 2003, 7, 75-81.

Suh, R. S.; Phadke, N.; Ohl, D. A.; Takayama, S.; Smith, G. D. "Rethinking Gamete/Embryo Isolation and Culture with Microfluidics" Hum. Reprod. Update 2003, 9, 451-461.

Lim, D.; Kamotani, Y.; Cho, B.; Mazumder, J.; Takayama, S. "Fabrication of Microfluidics Mixers and Artificial Vasculatures Using a High-Brightness Diode-Pumped Nd:YAG Laser Direct Write Method" Lab Chip 2003, 3, 318-323.

Huh, D.; Tkaczyk, A.H.; Bahng, J.-H.; Chang, Y.; Wei, H.-H.; Grotberg, J.B.; Kim, C.-J.; Kurabayashi, K.; Takayama, S. "Reversible Switching of High-Speed Air-Liquid Two-Phase Flows Using Electrowetting-Assisted Flow-Pattern Change" J. Am. Chem. Soc. 2003, 125, 14678-14679.

2002

Jiang, X.; Takayama S.; Qian, X.; Ostuni, E.; Wu, H.; Bowden, N.; LeDuc, P.; Ingber, D. E.; Whitesides, G. M. “Controlling Mammalian Cell Spreading and Cytoskeletal Arrangement with Conveniently Fabricated Continuous Wavy Features on Poly(dimethylsiloxane)” Langmuir, 2002; 18, 3273.

Huh, D; Tung, Y-C; Wei, H.-H.Grotberg, J.B.; Skerlos, S.J.; Kurabayashi, K.; Takayama, S. “Use of Air-Liquid Two-Phase Flow in Hydrophobic Microfluidic Channels for Disposable Flow CytometersBiomed. Microdev. 2002,4, 141-149.

Sawano, A.; Takayama, S.; Matsuda, M.; Miyawaki, A. “Lateral Propagation of EGF Signaling after Local Stimulation Is Dependent on Receptor Density” Dev. Cell, 2002, 3, 245-257.

2001

Takayama, S.; Ostuni, E.; Qian, X.; McDonald, J. C.; Jiang, X.; LeDuc, P.; Wu, M.-H.; Ingber, D. E.; Whitesides, G. M. "Topographical Micropatterning of Poly(dimethylsiloxane) Using Laminar Flows of Liquids in Capillaries" Adv. Mater. 2001, 13, 570-574.

Holmlin, R. E.;Chen, X.; Chapman, R.; Takayama, S.; Whitesides, G. M. "Zwitterionic SAMs that Resist Nonspecific Adsorption of Protein from Aqueous Buffer" Langmuir, 2001, 17, 2841-2850.

Takayama, S.; Ostuni, E.; LeDuc, P. Naruse, K.; Ingber, D. E.; Whitesides, G. M. "Laminar Flows: Subcellular Positioning of Small Molecules" Nature, 2001, 411, 1016.

Whitesides, G.M.; Ostuni, E.; Takayama, S.; Jiang, X "Soft Lithography for Biology" Ann. Rev. Biomed. Eng. 2001, 3, 335-373.

Ostuni, E; Chapman, R. G.; Holmlin, R. E.; Takayama, S.; Whitesides, G. M. "A Survey of Structure-Properety Relationships of Surfaces that Resist the Adsorption of Proteins" Langmuir, 2001, 17, 5605-5620.

2000

Takayama, S.; Chapman, R. G.; Kane, R. S.; Whitesides, G. M. "Patterning Cells and their Environment" Book chapter in Principles of Tissue Engineering, 2nd Ed. Lanza, R.; Langer, R.; Vacanti, J. 2000, 209-220.

Chapman, R. G.; Ostuni, E.; Takayama, S.; Holmlin, R. E.; Yan, L.; Whitesides, G. M. "Surveying for Surfaces that Resist the Adsorption of Proteins" J. Am. Chem. Soc. 2000, 122, 8303-8304.

Kenis, P. J. A.; Ismagilov, R. F.; Takayama, S.; Whitesides, G. M.; Li, S; White, H. S. "Microfabrication Inside Microchannels using Fluid Flow" Acc. Chem. Res. 2000, 33, 841-847.

1999

Takayama, S.; Lee, S. T.; Hung, S.-C.; Wong, C.-H. "Designing Enzymatic Resolution of Amines" Chem. Commun. 1999, 127-128.

Takayama, S.; Chung, S.-J.; Igarashi, Y.; Ichikawa, Y.; Sepp, A.; Lechler, R.I.; Wu, J.Y.; Hayashi, T, Siuzdak, G.; Wong, C.-H. "Selective Inhibition of b-1,4- and a-1,3-Galactosyltransferases: Donor Sugar-Nucleotide Based Approach" Bioorg. Med. Chem. 1999, 7, 401-409. 

Takayama, S.; McDonald, J. C.; Ostuni, E.; Liang, M. N.; Kenis, J. P. A.; Ismagilov, R. F.; Whitesides, G. M. "Patterning Cells and Their Environments Using Multiple Laminar Fluid Flows in Capillary Networks" Proc. Natl. Acad. Sci. USA 1999, 96, 5545-5548. 

Kane, R. S.; Takayama, S.; Ostuni, E.; Ingber, D. E.; Whitesides, G. M. "Patterning Proteins and Cells Using Soft Lithography " Biomaterials1999, 20, 2363-2376.

1998 

Takayama, S.; McGarvey, G. J.; Wong, C.-H. "Enzymes in Organic Synthesis: Recent Developments in Aldol Reactions and Glycosylations" Chem. Soc. Rev., 1998, 26, 407-415.

Wittmann, T.; Takayama, S.; Weitz-Schmidt, G.; Wong, C.-H. "Ligand Recognition by E- and P-Selectin: Chemoenzymatic Synthesis and Inhibitory Activity of Bivalent Sialyl Lewis X Derivatives and Sialyl Lewis X Carboxylic Acids" J. Org. Chem. 1998, 63, 5137-5143. 

Wischnat, R.; Martin, R.; Takayama, S.; Wong, C.-H. "Chemoenzymatic Synthesis of Iminocyclitol Derivatives: A Useful Library Strategy for the Development of Selective Fucosyltransfer Enzyme Inhibitors" Bioorg. Med. Chem. Lett. 1998, 8, 3353-3357. 

Chung, S. J.; Takayama, S.; Wong, C.-H. "Acceptor Substrate-Based Selective Inhibition of Galactosyltransferases" Bioorg. Med. Chem. Lett. 1998, 8, 3359-3364.

1997

Takayama, S.; Wong, C.-H. "Chemoenzymatic Approach to Carbohydrate Recognition" Curr. Org. Chem. 1997, 1, 109-126.

Takayama, S.; McGarvey, G. J.; Wong, C.-H. "MICROBIAL ALDOLASES AND TRANSKETOLASES: New Biocatalytic Approaches to Simple and Complex Sugars" Ann. Rev. Microbiol. 1997, 51, 285-310.

Wu, J., Takayama, S., Wong, C.-H., Siuzdak, G. "Quantitative Mass Spectrometry for the Rapid Assay of Enzyme Inhibitors" Chem. & Biol., 1997, 4, 653-657.

Takayama, S.; Martin, R.; Wu, J.; Laslo, K.; Siuzdak, G.; Wong, C.-H. "Chemoenzymatic Preparation of Novel Cyclic Imine Sugars and Rapid Biological Activity Evaluation Using Electrospray Mass Spectrometry and Kinetic Analysis" J. Am. Chem. Soc., 1997, 119, 8146-8151.

1996 and earlier

Takayama, S.; Shimazaki, M.; Qiao, L.; Wong, C.-H. "Synthesis of Lactosamine Derivatives Using b-D-Galactosidase from Bacillus circulans" Bioorg. Med. Chem. Lett. 1996, 6, 1123-1126. 

Jeong, J.-H.; Murray, B. W.; Takayama, S.; Wong, C.-H. "Cyclic Guanidino-Sugars with Low pKa as Transition-State Analog Inhibitors of Glycosidases: Neutral Instead of Charged Species Are the Active Forms" J. Am. Chem. Soc. 1996, 118, 4227-4234.

Lin, C.-C.; Shimazaki, M.; Heck, M.-P.; Aoki, S.; Wang, R.; Kimura, T.; Ritzen, H.; Takayama, S.; Wu, S.-H.; Weitz-Schmidt, G.; Wong, C.-H. "Synthesis of Sialyl Lewis X Mimetics and Related Structures Using Glycosyl Phoshite Methodology and Evaluation of E-Selectin Inhibition" J. Am. Chem. Soc. 1996, 118, 6826-6840. 

Takayama, S.; Livingston, P. O.; Wong, C.-H. "Synthesis of the Melanoma-associated Ganglioside 9-O-Acetyl GD3 Through Regioselective Enzymatic Acetylation of GD3 Using Subtilisin" Tetrahedron Lett., 1996, 37, 9271-9274. 

Murray, B. W.; Takayama, S.; Schultz, J.; Wong, C.-H. "Mechanism and Specificity of Human a-1,3-Fucosyltransferase V" Biochemistry, 1996, 34, 11183-11195. 

Kimura, T.; Takayama, S.; Huang, H.; Wong, C.-H. "A Novel and Practical Synthesis of N-Acetyl-D-lactosamine by the Tandem Use of Galactose Oxidase and b-D-Galactosidase" Angew. Chem. Int. Ed. Engl. 1996, 35, 2348-2350.

Mori, K.; Takayama, S.; Kido, M. "Reduction of Bicyclo[3.3.1]nonane-2,8-diones with Baker's Yeast", Bioorg. Med. Chem. 1994, 2, 395-401.

Mori, K.; Takayama, S.; Yoshimura, S. "Reduction of a Prochiral Diketone, 9-Methyl-trans-decalin-1,8-dione, with Baker's Yeast", Liebigs Ann. Chem. 1993, 91-95.
   

2002

Cho, B. Schuster,T.; Zhu, X.; Chang, D.; Smith, G.D.;  Takayama, S.  ”A Microfluidic Device for Separating Motile Sperm from Nonmotile Sperm via Inter-streamline Crossing” 2nd IEEE-EMBS Special Topics Conference on Microtechnologies in Medicine & Biology, May 2-4, 2002, Madison, WI, USA, 156-159.

Huh, D.; Wei, H.-H; Grotberg, J.B.; Takayama, S. “Development of Stable and Tunable High-Speed Liquid Jets in Microscale for Miniaturized and Disposable Flow Cytometry” 2nd IEEE-EMBS Special Topics Conference on Microtechnologies in Medicine & Biology, May 2-4, 2002, Madison, WI, USA (Invited talk), 449-452.

Huh, D.; Wei, H.-H.; Kripfgans, O.D.; Fowlkes, J.B.; Grotberg, J.B.; Takayama, S. “Gravity-Driven Microhydrodynamics-Based Cell Sorter (microHYCS) for Rapid, Inexpensive, and Efficient Cell Separation and Size-Profiling” 2nd IEEE-EMBS Special Topics Conference on Microtechnologies in Medicine & Biology, May 2-4, 2002, Madison, WI, USA, 466-469.

Lim, D.; Cho, B.; Takayama, S.; Mazumder, J. “Micromachining of Microfluidic Devices using a High-Brightness Diode-Pumped Nd:YAG Laser (P541)” 24th International Congress on Application of Lasers and Opto-electronics, Oct 14-17, 2002, Scottsdale AZ, USA

Shim, J.; Cui, X.; Martin, D. C.; Takayama, S. “Microfluidic electrochemical cell to pattern conducting polymer substratesfor the study of nerve guidance” 2nd IEEE-BMES Joint Meeting, Houston, TX, Oct 23-26, 2002.

Huh, D.; Tkaczyk, A. H.; Wei, H.-H.;Grotberg, J. B. ; Takayama, S. “Towards Portable Flow Cytometry: Study on the Use of Air-Sheath-Based Volume-Efficient Two-Phase Microfluidic Systems” 2nd IEEE-BMES Joint Meeting, Houston, TX, Oct 23-26, 2002.

Zhu, X.; Phadke, N.; Chang, J.; Cho, B.; Huh, D.; Takayama, S. “Gravity-Driven Microfluidic Pump with a Steady Flow Rate” Micro Total Analysis Systems 2002, Nara, Japan, Nov. 3-7, 2002, 151-153.

2001

Takayama, S.; Huh, D.; Shim, J. "Microdevices for Cell Biology" 3rd Korea MEMS Conference, Seoul National University, Korea, Apr 13-14, 2001, pp 31-34.

Huh, D; Tung, Y-C; Grotberg, J.B.; Skerlos, S.J.; Kurabayashi, K.; Takayama, S. "Air-Water Two-Phase Microfluidic System for Low-Cost, Low-Volume, and Low-Power Micro Flow Cytometer (uFC)" Micro Total Analysis Systems 2001, Monterey, CA, Oct. 22-25, 2001, 468-470.

Skerlos, S. J.; Adriaens, P.; Kurabayashi, K.; Takayama, S.; Hayes, K.; Rihana, A.; Zhao, F. "Challenges to Sustainable Aqueous Systems: A Case Study in Metalworking Fluids" EcoDesign 2001, Tokyo, Japan, Dec 11-15, 2001. IEEE Computer Society Press.

2000

Takayama, S.; Ostuni, E.; Qian, X.; McDonald, J. C.; Jiang, X.; LeDuc, P.; Wu, M.-H.; Ingber, D. E.; Whitesides, G. M. "Patterning the Topographical Environment for Mammalian Cell Culture Using Laminar Flows in Capillaries" 1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology, Lyon, France, Oct 12-14, 2000, pp 322-325.