Cellular chirality arising from the self-organization of the actin cytoskeleton. Y.H. Tee, T. Shemesh, V. Thiagarajan, R.F. Hariadi, K.L. Anderson, C. Page, N. Volkmann, D. Hanein, S. Sivaramakrishnan, M.M. Kozlov, A.D. Bershadsky. Nature Cell Biology 2015, 17(4), 445-57. Full Text: Link   PDF   Cover


The C2 domain and altered ATP-binding loop phosphorylation at Ser359 mediate the redox-dependent increase in Protein Kinase Cδ activity. J. Gong, Y. Yao, P. Zhang, B. Udayasuryan, E.V. Komissarova, J. Chen, S. Sivaramakrishnan, J.E. Van Eyk, S.F. Steinberg. Molecular and Cellular Biology Mar 9. 2015, [Epub date].
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Tuning myosin-driven sorting on cellular actin networks. R.F. Hariadi, R. Sommese, S. Sivaramakrishnan eLife 2015, Mar 4, 4. Full Text: Link   PDF


A method for multiprotein assembly in cells reveals independent action of kinesins in complex. S. R. Norris, V. Soppina, A. S. Dizaji, K. I. Schimert, D. Sept, D. Cai, S. Sivaramakrishnan, and K. J. Verhey Journal of Cell Biology 2014, 207(3), 393-406. Full Text: Link   PDF


Optofluidic lasers with a single molecular layer of gain. Q. Chen, M. Ritt, S. Sivaramakrishnan, Y.A. Sun and X. Fan Lab Chip 2014, Oct. 2nd [Epub date].
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Natural Killer Cells Eradicate Galectin-1-Deficient Glioma in the Absence of Adaptive Immunity. C.J. Baker, P. Chockley, V.N. Yadav, R. Doherty, M. Ritt, S. Sivaramakrishnan, M.G. Castro, and P.R. Lowenstein. Cancer Research 2014, 15;74(18), 5079-90. Full Text: Link   PDF


Harnessing the unique structural properties of isolated α-helices. C.J. Swanson and S. Sivaramakrishnan Journal Biological Chemistry 2014, 12;289(37), 25460-7. Full Text: Link   PDF


Conserved Modular Domains Team Up to Latch-Open Active PKCα. C.J. Swanson, M. Ritt, W. Wang, M. Lang, A. Narayan, J. Tesmer, M. Westfall, S. Sivaramakrishnan Journal Biological Chemistry 2014, 289(25), 17812-29.
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Myosin lever arm directs collective motion on cellular actin network. R.F. Hariadi, M. Cale, and S. Sivaramakrishnan Proceedings of the National Academy of Sciences 2014, 111(11), 4091-6.
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Analyses of conformational states of the transporter associated with antigen processing (TAP) in a native cellular membrane environment J. Geng, S. Sivaramakrishnan and M. Raghavan Journal Biological Chemistry 2013, 288, 37039-47.
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Agonist Activated PKCβII Translocation and Modulation of Cardiac Myocyte Contractile Function. H. Hwang, D. Robinson, J. B. Rogers, T. K. Stevenson, S. E. Lang, S. Sadayappan, S. M. Day, S. Sivaramakrishnan S, M. V. Westfall. Scientific Reports 2013, 3, 1971.
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Detection of G Protein-selective G Protein-coupled Receptor (GPCR) Conformations in Live Cells. R.U. Malik , M. Ritt, B.T. Devree, R.R. Neubig, R.K. Sunahara, S. Sivaramakrishnan. Journal of Biological Chemistry 2013, 288(24), 17167-78.
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Highly sensitive fluorescent protein FRET detection using optofluidic lasers. Q. Chen , X. Zhang , Y. Sun , M. Ritt , S. Sivaramakrishnan and X. Fan. Lab on a Chip 2013, 13(14), 2679-81.
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Visualizing and manipulating focal adhesion kinase regulation in live cells. M. Ritt, J.L. Guan, S. Sivaramakrishnan. Journal of Biological Chemistry 2013, 288(13), 8875-86.
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Cell-intrinsic functional effects of the α-cardiac myosin Arg-403-Gln mutation in familial hypertrophic cardiomyopathy. P. Chuan, S. Sivaramakrishnan, E.A. Ashley, J.A. Spudich. Biophysical Journal 2012, 102(12), 2782-2790.
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Dual-beam optical tweezers. S. Sivaramakrishnan, J. Sung, A. Dunn, J.A. Spudich. Encyclopedia of Biophysics, Ed. Gordon Roberts, Springer.
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Systematic control of protein interaction using a modular ER/K α-helix linker. S. Sivaramakrishnan, J. A. Spudich, Proceedings of the National Academy of Sciences, USA 2011, 108(51), 20467-72.
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Principles of unconventional myosin function and targeting. M. Hartman, D. Finan, S. Sivaramakrishnan, J. A. Spudich, Ann. Rev. Cell Dev. Biol 2011, 27, 133-55.
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Helicity of short E-R/K peptides. R. F. Sommese, S. Sivaramakrishnan, R. L. Baldwin, and J. A. Spudich, Protein Science 2010, 19(10), 2001-5.
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Single-molecule dual-beam optical trap analysis of protein structure and function. J. Sung, S. Sivaramakrishnan, A. Dunn, J.A. Spudich, Methods in Enzymology 2010, 475, 321-75.
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Myosin VI: an innovative motor that challenged the swinging lever arm hypothesis. S. Sivaramakrishnan, J.A. Spudich, Nature Reviews: Molecular and Cellular Biology 2010, 11(2), 128-37
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Combining single molecule optical trapping and small angle X-ray scattering measurements to compute the persistence length of a protein ER/K alpha-helix. S. Sivaramakrishnan, J. Sung, M. Ali, S. Doniach, H. Flyvbjerg, J. A. Spudich, Biophysical Journal 2009, 97(1-7), 2993-9
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Coupled myosin VI motors facilitate unidirectional movement on an F-actin network. S. Sivaramakrishnan, J.A. Spudich, Journal of Cell Biology 2009, 187(1), 53-60
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Insights into human beta-cardiac myosin function from single molecule and single cell studies. S. Sivaramakrishnan, E. Ashley, L. Leinwand, J.A. Spudich, Journal of Cardiovascular Translational Research (Springer New York), Invited Review, Epub Sep. 25th, 2009.
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Dynamic charge interactions create surprising rigidity in the ER/K alpha-helical protein motif. S. Sivaramakrishnan, B. J. Spink, A. Y. L. Sim, S. Doniach, J. A. Spudich, Proceedings of the National Academy of Sciences, USA, 2008, 105(36), 13356-61.
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Long single alpha-helical tail domains bridge the gap between structure and function of myosin VI. B.J. Spink, S. Sivaramakrishnan, J. Lipfert, S. Doniach, J.A. Spudich, Nature: Structural and Molecular Biology, 2008, 15(6), 591-97.
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6 - 31 of 31 Publications

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