563 Full-mouth disinfection in the treatment of periodontitis in diabetic subjects

Thursday, March 22, 2012: 3:30 p.m. - 4:45 p.m.
Presentation Type: Poster Session
V.R. SANTOS, J.A. LIMA, T.S. MIRANDA, M. FAVERI, and P.M. DUARTE, Department of Periodontology, Guarulhos University, Guarulhos, Brazil
Objectives: The aim of this study was to evaluate the clinical and glycemic effects of chlorhexidine as an adjunct to a full-mouth disinfection (FMD) protocol in type 2 diabetic subjects with generalized chronic periodontitis. 

Methods: Thirty-seven subjects were randomly assigned in: Test group (FMD; n=19) - scaling and root planing (SRP) within 24 hours + local application of chlorhexidine gel + chlorhexidine rinses for 60 days; Control group (n=18): SRP within 24 hours + local application of placebo gel + placebo rinses for 60 days. Periodontal clinical parameters, glycated hemoglobin and fasting plasma glucose levels were assessed at baseline, 3, 6 and 12 months post-therapies.

Results: All clinical parameters improved significantly at 3, 6 and 12 months post-therapies (P <0.05). There were no significant differences between therapeutic groups for any clinical and glycemic parameter at any time-point (P >0.05).

Conclusions: Both therapies were equally effective in treating chronic periodontitis in type 2 diabetic subjects, without significant improvements in the glycemic control at any time-point.

This abstract is based on research that was funded entirely or partially by an outside source: São Paulo State Research Foundation: # 2008/11419-4

Keywords: Antimicrobials, Clinical trials, Diabetes, Effectiveness and Periodontal disease