1140 Bone healing with Low-Level Laser Therapy

Friday, March 23, 2012: 3:30 p.m. - 4:45 p.m.
Presentation Type: Poster Session
N. CAMPOS1, M.J. NAGATA2, M.R. MESSORA3, N.M. POLA1, S.E. FUCINI4, C.S. SANTINONI1, A.F. BOSCO2, and V.G. GARCIA2, 1Surgery and Integrated Clinic, Univ. Estadual Paulista - UNESP, Arašatuba-SP, Brazil, 2Department of Surgery and Integrated Clinic - Division of Periodontics, Univ. Estadual Paulista - UNESP, Arašatuba-SP, Brazil, 3Lavras-MG, Brazil, 4Private Practice, Hanover, NH
Objectives: The purpose of this study was to histomorphometrically analyze the influence of Low-Level Laser Therapy (LLLT) on bone healing in surgically created critical-size defects (CSD) in rat calvaria.

Methods:  Twenty rats were divided into 2 groups: Group C (control) and Group LLLT. A 5 mm diameter CSD was created in the calvarium of each animal. In Group C, the defect was filled by blood clot only. In Group LLLT, the defect received laser irradiation, it was filled with blood clot and then it was irradiated again. All animals were euthanized 30 days postoperative. Histometric, using image analysis software, and histologic analyses were performed. Amount of newly formed bone was calculated as a percentage of the total area of the original defect. Percentage data were transformed into arccosine for statistical analysis (ANOVA one way, Tukey, p<0.05).

Results:  No defect completely regenerated with bone. Group LLLT (17.27% ± 6.96%) had statistically greater amount of bone formation than Group C (12.74% ± 4.53%).

Conclusions:  LLLT significantly enhanced bone healing in surgically created CSD in rat calvaria.

This abstract is based on research that was funded entirely or partially by an outside source: Carolina S. Santinoni received a scholarship from FAPESP (Proc. 10/04450-2)

Keywords: Bone repair, Implantology, Lasers and Periodontics