YANG Laboratory

Biophysics of Living Systems

Teaching

  • Physics/Biophysics 608: Biophysical Principles of Microscopy

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    Instructor: Qiong Yang


    Description: This course covers the fundamental physics and math behind optical microscopy. An emphasis is on physical principles of a variety of advanced optical imaging techniques, including super-resolution imaging, FCS, FRET, FLIM, SPIM, and nonlinear microscopies, as well as their applications in biological sciences. The physics and math level will assume some familiarity with geometrical and physical optics and complex exponential notation.



  • Biophysics 435/535: Biophysical Modeling

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    Instructor: Qiong Yang


    Description: This course covers the basic concepts of biophysical modeling which applies the biophysical approach to modeling biological systems. A survey of problems ranges from biochemical reactions, regulatory networks, bistable switches, oscillations, random processes, Brownian dynamics, reaction-diffusion problems, collective behavior and pattern formation. We discuss modeling these problems by introducing techniques of nonlinear dynamics, ODE/DDE/PDE, stability analysis, bifurcation theory and synchronization, numerical methods, molecular dynamics simulation, as well as stochastic modeling.



  • Biophysics/Chemistry/Physics 417: Dynamical Processes in Biophysics

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    Instructor: Qiong Yang


    Description: This course covers the basic physics behind many biological processes. Modules cover diffusion, electrophysiology, biopolymer elasticity, and molecular motors. Two basic themes that resurface throughout the course are the universality of diffusive behavior and the role of energy consumption in driving non-equilibrium processes. The course includes an introduction to reading the primary scientific literature.



  • Biophysics 450/550 Biological Chemistry 416/516 Physics 450: Techniques in Biophysics

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    Instructor: Qiong Yang


    Description: This hands-on laboratory course teaches essential laboratory skills in biophysics and biochemistry. Experiments cover protein expression and purification; computational methods such as molecular dynamics simulation and three-dimensional visualization methods of protein structures; modern research methods such as optical tweezers, fluctuation correlation spectroscopy, live cell fluorescence microscopy, and circular dichroism; and the assembly of bright-field microscope. A final project will allow students to explore a topic of their interest in greater depth.