Coronal sections through the adult rat dentate gyrus are immunostained for doublecortin (DCx), a microtubule-associated protein expressed by immature neurons.  In a control (A), DCx expression is confined to the typical region of persistent neurogenesis (arrows) in cells at the border of the inner dentate granule cell layer (dgc) and hilus (h). Two weeks after pilocarpine-induced status epilepticus (B), DCx expression is increased at the dgc/hilar border (arrows), and is present in cells of the hilus and inner molecular layer (arrowheads). This “ectopic” DCx expression is seen only after seizure-induced injury and suggests aberrant neurogenesis.