| UMCC 9555 | PhaseIIb Chemoprevention Trial of
Difluoromethylornithine (DFMO) in Human Subjects with Intestinal-type Barrett’s Esophagus (Brenner) |
Completed |
| UMCC 9609 | Retinoids
and Intermediate Biomarkers for
CIN II and III (Ruffin) |
Completed |
| UMCC 9644 | Radiotherapy
and Gemcitabine for Chest
Wall Recurrences in the Treatment of Breast Cancer (Pierce) |
Completed |
| UMCC 9727 | Hearing
loss in Patients Undergoing
Irradiation (RT) to the Auditory Pathways (Eisbruch) |
Completed |
| UMCC
9759 |
Assessment
of the Quality of Life of
Patients with Head and Neck Cancer Irradiated with Parotid Sparing or
Standard Techniques (Eisbruch) |
Completed |
| UMCC 9941 | Phase I Pharmacokinetic Trial of Curcuminoids Administered in a Capsule Formulation (Brenner) | Completed |
| UMCC 9961 | Hyperfractionated Radiation and Gemcitabine for Advanced Head and Neck Tumors (Eisbruch) | Completed |
| UMCC
9974 |
Pilot Study of On-Line
Imaging During Radiotherapy (Eisbruch) |
Completed |
| UMCC 9976 | A Phase I Trial of
Cisplatin plus Gemcitabine and Radiation
Therapy in Pancreatic Cancer (McGinn) |
Completed |
| GCRC 1633 |
Radioiodine Treatment
& Graves' Eye Disease (Sisson) |
Open |
| UMCC 2000-004 | The Tolerance and
Reproducibility of Lung Tumor
Immobilization Using Active Breathing Control (Hayman) |
Open |
| UMCC 2000-008 | A Study of Early Tumor
Response Assessment and Modification
of Head and Neck Cancer Irradiation Plans Using Diffusion MRI (Eisbruch) |
Open |
| UMCC
2000-046 |
Phase II Trial of
Preoperative Radiation Therapy with
Capecitabine in Rectal Cancer (Zalupski) |
Open |
| UMCC 2000-088 | A Phase I Study of High Dose Conformal Three‑Dimensional Irradiation in a Shortened Time Interval for Medically Inoperable Stage I Lung Cancer (Henning) | Never Opened |
| UMCC 2000-147 | GLNE 001: Preliminary Clinical Characterization of Serum, Plasma and Urine Biomarkers for Colorectal Neoplasms (Brenner) | Open |
| UMCC 2001-008 | A Phase II Study of High
Dose Radiation (Combined with
Hepatic Arterial Floxuridine) for Patients with Unresectable
Intrahepatic Malignancies (Lawrence) |
Completed |
| UMCC 2001-046 | Pilot Trial of Capecitabine and Radiation Therapy with Pre and Post Combination Chemotherapy in Advanced Pancreatic Cancer (Zalupski) | Completed |
| UMCC
2001-054 |
Phase
I Clinical Trial
of Black Raspberries for Prevention of Colorectal Cancer (Brenner) |
Never Opened |
| UMCC 2001-061 | A Phase II Trial of Full-Dose Gemcitabine with Concurrent Radiation Therapy in Patients with Resectable or Unresectable Non-Metastatic Pancreatic Cancer (McGinn) | Completed |
| UMCC 2002-008 | Phase I Trial of Dose
Escalated Whole Liver Irradiation with
Hepatic Arterial Floxuridine / Leucovorin / Streptozotocin Chemotherapy
Followed Subsequently by Chemoembolization with Mitomycin-C for
Patients with Neuroendocrine Hepatic Metastases (Ensminger) |
Open |
| UMCC 2002-014 | A Phase I Whole Liver
Radiation Dose Escalation Trial Using
Amisfostine as a Radioprotective Agent (Lawrence) |
Closed |
| UMCC 2002-021 | Optimized Intensity
Modulated Irradiation for Head and Neck
Cancer (Eisbruch) |
Open |
| UMCC 2002-054 | A Pilot Study to
Quantify and Compare the Volume of Target
and Normal Tissue Irradiated Using Sequential MRI-CT Fusion, Video
Fluoroscopy, and Daily Portal Imaging in Radiation Therapy Treatment
Planning for Cervical Cancer (Pan) |
Open |
| UMCC 2002-066 | Phase I Study of
Concurrent Temozolomide and 3D Conformal
Radiotherapy Dose Escalation for Treatment of High Grade Gliomas
(Tsien) |
Open |
| UMCC 2003-008 | GLNE 003: Preliminary Validation of Biomarkers Predictive of Barrett's Esophagus Progression to Dysplasia and Adenocarcinoma (Brenner) | Open |
| UMCC 2003-023 | Phase I Study of
Concurrent Gemcitabine and Radiotherapy for
Malignant High Grade Gliomas (Tsien) |
Open |
| UMCC
2003-032 |
PET in Whole Brain
Radiation (Tsien) |
Open |
| UMCC 2003-039 | Quantification of Set-Up
Uncertainty and Organ Motion Due to
Breathing in Breast Cancer Patients (Pierce) |
Open |
| UMCC 2003-042 | GLNE 005: Preliminary Characterization of Colorectal Flat Adenomas (Brenner) | Completed |
| UMCC 2003-043 | GLNE 006: Preliminary Characterization of Colorectal Flat Polyps Identified by Chromoendoscopy in Subjects with Hereditary Nonpolyposis Colorectal Cancer (Brenner) | Completed |
| UMCC
2003-050 |
Assessing Cognitive
Function in
Women with Breast Cancer Using Functional Magnetic Resonance Imaging: A
Feasibility Study (Cimprich) |
Completed |
| UMCC 2003-052 |
Feasibility
of
Barrett's
Esophagus Chemoprevention Through Evaluation of Esophageal Resections
(Lao) |
Never Opened |
| UMCC
2003-064 |
Phase
I Single-Dose
Safety and Pharmacokinetics Clinical
Study of Resveratrol (Abrams, Brenner, Gescher) |
Completed |
| UMCC 2003-067 | A Randomized, Phase II
Trial of Urethral Sparing
Intensity-Modulated Radiation Therapy (US-IMRT) compared to Standard 3D
Conformal Radiation Therapy (3D-CRT) for Low-risk Prostate Cancer
Patients to improve Quality of Life (QOL) within the Urinary Domain as
measured by the Expanded Prostate Cancer Index Composite (EPIC)
(Sandler) |
Closed |
| UMCC
2003-072 |
A Pilot Study of Radiation-Induced Liver Disease Onset Using CT-based Perfusion (Ben-Josef) | Open |
| UMCC 2003-073 | A Phase I/II Randomized
Trial in Radiation Dose Escalation
and Timing of Concurrent Chemotherapy for Patients with Stage III
Unresectable/Inoperable Non-Small Cell Lung Cancer (Kong) |
Closed |
| UMCC
2003-076 |
A Pilot Study to
Evaluate the Impact of Multiple Functional
Images on Radiation Treatment Planning and Radiation Lung Toxicity
Prediction (Kong) |
Completed |
| UMCC 2003-081 | Assessment of Liver
Function in Patients Undergoing Hepatic
Irradiation (Ben-Josef) |
Open |
| UMCC 2003-082 | Gemcitabine,
Oxaliplatin and Radiation Therapy in Pancreatic
Cancer (Zalupski) |
Completed |
| UMCC 2003-083 | MRI Study of
Radiation-Induced Damage to White Matter and
Blood-Brain-Barrier (Cao) |
Open |
| GCRC 1935 | Randomized Placebo-Controlled Study of Methods to Blind Study Participants to Encapsulated Ginger Aroma (Zick) | Completed |
| GCRC 1956 | Human Papillomavirus in Men "HiM": Pilot Study (Ruffin) | Completed |
| UMCC 2004-024 | A Pilot Study of
[F-18]FLT-PET in Patients with Head and Neck
Cancer Undergoing Chemo-Irradiation (Eisbruch) |
Open |
| UMCC 2004-029 | Pilot Study of ZD1839
(Iressa) and Intensity Modulated
Radiotherapy (IMRT) in Recurrent Gliomas (Tsien) |
Open |
| UMCC 2004-032 | Pilot study to evaluate the feasibility of MR colonography with oral fecal tagging in the detection of colorectal lesions (Adusumilli) | Completed |
| UMCC 2004-038 | A Randomized Comparison of Radiation Therapy Techniques in the Management of Node Positive Breast Cancer (Pierce) | Open |
| GCRC 1916 | HPV Infection and High Fruit and Vegetable Diet (HIgh FiVeD): Pilot (Ruffin) | Open |
| UMCC 2005-003 | MRI Study of Changes in Blood-Brain/Tumor-Barrier Permeability in Patients with Brain Metastases During and After Radiotherapy (Cao) | Open |
| UMCC 2005-008 | GLNE 007: Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas (Brenner) | Open |
| UMCC
2005-013 |
A Pilot Sudy of
Pancreatic Motion in Patients Undergoing
Radiation Therapy for Pancreatic Cancer (Ben-Josef) |
Completed |
| UMCC 2005-015 | A Pilot Trial To Determine The Effect Of Intratreatment Organ Motion On The Minimum Dose To The Prostate During External Beam Prostate Radiotherapy (Sandler) | Open |
| UMCC 2005-065 | Pilot study to assess EGFR inhibition by erlotinib in tumors as compared with normal mucosa in patients with locally advanced squamous cell carcinoma of the head and neck (Tsien) | Open |
| UMCC 2005-084 | A Pilot Study of Tumor and Critical Normal Tissue Motion in Head and Neck Cancer Using Cone Beam CT (Eisbruch) | Open |
| UMCC 2005-132 | A Phase II Study of Focal Liver Irradiation Using IMRT with Concurrent Hepatic Arterial Floxuridine for Unresectable Intrahepatic Malignancies (Pan) | Never Opened |
| UMCC 2005-137 | Phase I/II Dose Escalation Study of Oral D-Methionine and Chemoradiation to Reduce Oral Mucositis in Head and Neck Cancer Patients (Eisbruch) | Never Opened |
| UMCC 2006-018 | A Phase I Radiation Dose-Escalation Study Of Intensity-Modulated Radiotherapy (IMRT) With Concurrent Gemcitabine In Patients With Unresectable Pancreatic Cancer (Ben-Josef) | Open |
| UMCC 2006-025 | A Multi-Institutional Phase II Study of Neoadjuvant Gemcitabine and Oxaliplatin with Radiation Therapy in Patients with Pancreatic Cancer (Zalupski) | Open |
| UMCC 2006-040 | Using Functional Image and Circulating Molecular Markers to Predict Tumor Response and Lung Toxicity in Treatment of Non-Small Cell Lung Cancer (Kong) | Open |
| UMCC 2006-047 | A Phase I Study Evaluating VELCADE as a Radiosensitizer in Patients with Metastatic Melanoma to the Brain who Require Whole Brain Radiation (Redman) | Open |
| UMCC 2006-067 | A Pilot Study of Radiation Toxicity Using MRI-based Perfusion (Pan) | Open |
| UMCCOP 02-01 | Phase II Trial of
Encapsulized Ginger as a Treatment for
Chemotherapy-Induced Nausea and Vomiting (Zick) |
Completed |
| GCRC 2018 | Single Dose Pharmacokinetic Trial of an Encapsulated Ginger Standardized to 5%-6-Gingerols (Zick) | Completed |
| Resveratrol
Task
1 Pilot |
Pilot
Study Phase I Single-Dose Safety and Pharmacokinetics Clinical Study of
Resveratrol (Boocock, Brenner) |
Completed |
| Resveratrol Task 2A PK | Phase I Repeat-Dose Clinical Study of Safety, Pharmacokinetics and Pharmacodynamics of Resveratrol (Boocock, Brenner) | Completed |
| Resveratrol Task 2B PD | Phase I Repeat-Dose Study of Resveratrol in Colorectal Cancer Patients: Tolerability, Target Tissue Levels and Pharmacodynamics (Boocock, Brenner) | Completed |
| UMVA 0008 | Phase II Study of Hypofrctionated Radiation Therapy For Patients With Localized Prostate Cancer (Elshaikh) | Never Opened |
| UMCC 2006-040 | Using
Functional Image and Circulating Molecular Markers to Predict Tumor
Response and Lung Toxicity in Treatment of Non-Small Cell Lung Cancer (Kong) |
Open |
| UMCC 2006-075 | Altered Brain Function in Chemotherapy for Breast Cancer (Cimprich) | Open |
| UMCC 2006-098 | A Phase I/II Study of Enzastaurin, Gemcitabine and Radiotherapy for Locally Advanced Unresectable Pancreatic Cancer (Ben-Josef) | Never Opened |
| UMCC 2006-106 | Saw Palmetto During Radiation Therapy for Prostate Cancer: A Phase I/II Study (Debiose) | Never Opened |
| UMCC 2007-AAA | A Phase II Study of Oral D-Methionine to Reduce Oral Mucositis in Patients Undergoing Chemoradiation for Head and Neck Cancer (Hamstra) | Under Review |
| GCRC 2246 | A Phase II Study of the Effect of Ginger Root on Markers of Inflammation in Gut Mucosa (Zick) | Open |
| UMCC 2007-017 | A Pilot Study of [18F] FLT-PET in Patients With
Resectable Pancreatic Cancer Uundergoing Neoadjuvant Chemoradiotherapy (Ben-Josef) |
Open |
| UMCC 2007-025 | GLNE 008: Preliminary Longitudinal Validation of Biomarkers Predictive of Barrett’s Esophagus Progression to Dysplasia and Adenocarcinoma (Brenner) | Open |
| UMCC 2007-029 | A Phase II Organ PreservationTrial Using Cetuximab and Radiation Therapy in Advanced Laryngeal Cancer Patients Who Have Responded to One Cycle of Induction Chemotherapy with Taxotere, Cisplatin, 5-Fluorouracil (TPF), and Cetuximab (Worden) | Closed |
| UMCC 2007-037 | Women's Healthy Lifestyle Study (Longworth) | Under Review |
| UMCC 2007-047 | Assessment of Neuronal Synaptic CNS Markers by Neurotransmitter PET in Patients with Neuro-Cognitive Decline after Radiation Treatment (Tsien) | Open |
| UMCC 2007-123 | Using FDG-PET Acquired During the Course of Radiation Therapy to Individualize Adaptive Radiation Dose Escalation in Patients with Non-Small Cell Lung Cancer (Kong) | Open |
| UMCC 2008-038 | A Pilot Study of Diffusion MRI in the Assessment of Pancreatic Tumor Response (Cao) | Open |
| UMCC 2009-009 | A Phase II Study of RT Concurrent with Cetuximab in Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma Who Do Not Qualify For Standard Chemotherapy Due To Age>70 Or Co-Morbidities (Jolly) | Open |