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Older Papers
about slow-aging mice: [Review] Miller, R. A., S. Austad, D. Burke, C. Chrisp, R. Dysko, A. Galecki, A. Jackson, and V. Monnier. 1999. Exotic mice as models for aging research: polemic and prospectus. Neurobiology of Aging 20:217-231. [PubMed] Miller, R. A. and S. Austad. 1999. Large animals in the fast lane (letter). Science 285:199. Miller, R. A., R. Dysko, C. Chrisp, R. Seguin, L. Linsalata, G. Buehner, J. M. Harper and S. Austad. 2000. Mouse stocks derived from tropical islands: new models for genetic analysis of life history traits. J. Zoology 250:95-104. Miller, R. A., C. Chrisp, and W. Atchley. 2000. Differential longevity in mouse stocks selected for early life growth trajectory. J. Gerontol. Biol. Sci. 55A:B455-B461. [PubMed] Flurkey, K., J. Papaconstantinou, R. A. Miller, and D. E. Harrison. 2001. Life span extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proc. Natl. Acad. Sci. USA 98:6736-6741. [PubMed] Bartke, A., J. C. Wright, J. A. Mattison, D. K. Ingram, R. A. Miller, and G. S. Roth. Extending the lifepan of long-lived mice. 2001. Nature 414: 412. [PubMed] [Review] Miller, R. A. Genetics of increased longevity and retarded aging in mice. 2001. Handbook of the Biology of Aging, 5th Edition; E. J. Masoro and S. N. Austad, editors; Academic Press, NY. Chapter 14, pp. 369 – 395. Miller, R. A., J. M. Harper, R. C. Dysko, S. J. Durkee, and S. N. Austad. 2002. Longer life spans and delayed maturation in wild-derived mice. Experimental Biology and Medicine 227:500-508. [PubMed] Bartke, A. J. C. Wright, J. A. Mattison, D. K. Ingram, R. A. Miller, and G. S. Roth. Letter: Dietary restriction and life span. 2002. Science 296: 2141 – 2142. [PubMed] Vergara, M., M. Smith-Wheelock, J. M. Harper, R. Sigler, and R. A. Miller. 2004. Hormone-treated Snell dwarf mice regain fertility but remain long-lived and disease resistant. J. Gerontol. Biol. Sci. 59:1244-1250. [PubMed] Harper, J. M., S. J. Durkee, M. Smith-Wheelock and R. A. Miller. 2005. Hyperglycemia, impaired glucose tolerance and elevated glycated hemoglobin levels in a long-lived mouse stock. Experimental Gerontology 40: 303- 314. [PubMed] Miller, R. A., G. Buehner, Y. Chang, J. M. Harper, R. Sigler, and M. Smith-Wheelock. 2005. Methionine-deficient diet extends mouse life span, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance. Aging Cell 4:199-125. [PubMed] Hulbert, A. J., S. C. Faulks, J. M. Harper, R. A. Miller, R. Buffenstein. 2006. Extended longevity of wild-derived mice is associated with peroxidation-resistant membranes. Mechanisms of Ageing and Development 127:653 – 657. [PubMed] Harper, J. M., S. J. Durkee, R. C. Dysko, S. N. Austad and R. A. Miller. 2006. Genetic modulation of hormone levels and life span in hybrids between laboratory and wild-derived mice. J. Gerontol. A Biol. Sci. Med. Sci. 61: 1019 - 1029. [PubMed] Older papers about cell stress resistance and aging: Murakami, S., A. Salmon, and R. A. Miller. 2003. Multiplex stress resistance in cells from long-lived dwarf mice. FASEB Journal express article 10.1096/fj.02-1092fje. FASEB Journal 17: 1565-1566. [PubMed] Salmon, A. B., S. Murakami, A. Bartke, J. Kopchick, K. Yasumura, and R. A. Miller. 2005. Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress. American Journal of Physiology: Endocrinology and Metabolism 289:E23-E29. [PubMed] Maynard, S. P., and R. A. Miller. 2006. Fibroblasts from long-lived Snell dwarf mice are resistant to oxygen-induced cell growth arrest in vitro. Aging Cell 5: 89 – 96. [PubMed] (*) Leiser, S. F., (*) A. B. Salmon, and R. A. Miller. 2006. Correlated resistance to glucose deprivation and cytotoxic agents in fibroblast cell lines from long-lived pituitary dwarf mice. (*) joint first authors. Mechanisms of Ageing and Development 127:821 - 829. [PubMed] Harper, J. M., A. B. Salmon, Y. Chang, M. Bonkowski, A. Bartke and R. A. Miller. 2006. Stress resistance and aging: Influence of genes and nutrition. Mech. Ageing Dev. 127:687 – 694. [PubMed] Salmon, A. B., M. Ljungman, and R. A. Miller. 2008. Cells from long-lived mutant mice exhibit enhanced repair of ultraviolet lesions. J. Gerontol. Biol. Sci. 63: 219 - 231. [PubMed] Swindell, W. R., M. M. Masternak, J. J. Kopchick, C. A. Conover, A. Bartke, and R. A. Miller. 2009. Endocrine regulation of heat shock protein mRNA levels in long-lived dwarf mice. Mechanisms of Aging and Development 130:393-400. [PubMed] Older
papers about T cell activation: Eisenbraun, M. D., A. Tamir, and R. A. Miller. 2000. Altered composition of the immunological synapse in an anergic, age-dependent memory T cell subset. J. Immunology 164:6105-6112. [PubMed] Tamir, A., M. D. Eisenbraun, G. G. Garcia, and R. A. Miller. 2000. Age-dependent alterations in the assembly of signal transduction complexes at the site of T cell/APC interaction. J. Immunol. 165:1243-1251. [PubMed] Garcia, G. G., and R. A. Miller. 2001. Single-cell analyses reveal two defects in peptide-specific activation of naïve T cells from aged mice. J. Immunol. 166:3151-3157. [PubMed] Garcia, G. G., and R. A. Miller. 2002. Age-dependent defects in TCR-triggered cytoskeletal rearrangement in CD4+ T cells. J. Immunol. 169:5021-5027. [PubMed] Garcia, G. G., and R. A. Miller. 2003. Age-related defects in CD4+ T cell activation reversed by glycoprotein endopeptidase. European Journal of Immunology 33:3464 - 3472. [PubMed] Garcia, G. G., S. B. Berger, A. A. Sadighi Akha, and R. A. Miller. 2005. Age-associated changes in glycosylation of CD43 and CD45 on mouse CD4 T cells. Eur. J. Immunol. 35: 622-631. [PubMed] [Review] Miller, R. A., S. B. Berger, D. T. Burke, A. Galecki, G. G. Garcia, J. M. Harper, and A. A. Sadighi-Akha. 2005. T cells in aging mice: genetic, developmental and biochemical analyses. Immunological Reviews 205: 94 – 103. [PubMed] [Review] Sadighi Akha, A., and R. A. Miller. 2005. Signal transduction in the aging immune system. Current Opinion in Immunology 17:486 - 491.. [PubMed] Sadighi Akha, A. A., S. B. Berger, R. A. Miller. 2006. Enhancement of CD8 T cell function through modifying surface glycoproteins in young and old mice. Immunology 119: 187 - 194. [PubMed] Berger, S. B., A. A. Sadighi Akha, R. A. Miller, and G. G. Garcia. 2006. CD43-independent augmentation of mouse T cell function by glycoprotein cleaving enzymes. Immunology 119: 178 - 186. [PubMed] Garcia, G. G., A. A. Sadighi Akha, and R. A. Miller. 2007. Age-related defects in moesin/ezrin cytoskeletal signals in mouse CD4 T cells. J. Immunol. 179: 6403-6409. [PubMed] Older papers about biomarkers of aging: Miller, R. A. 1997. Age-related changes in T cell surface markers: a longitudinal analysis in genetically heterogeneous mice. Mechanisms of Ageing and Development 96:181-196. [PubMed] Miller, R. A., C. Chrisp, and A. Galecki. 1997. CD4 memory T cell levels predict lifespan in genetically heterogeneous mice. FASEB Journal 11:775-783. [PubMed] Miller, R. A. 2001. Biomarkers of aging: prediction of longevity using age-sensitive T cell subset determinations in a middle-aged, genetically heterogeneous mouse population. J. Gerontol. Biol. Sci. 56A:B180-B186. [PubMed] Miller, R. A. and C. Chrisp. 2002. T cell subset patterns that predict resistance to spontaneous lymphoma, mammary adenocarcinoma, and fibrosarcoma in mice. J. Immunol. 169:1619-1625. [PubMed] Miller, R. A., J. M. Harper, A. Galecki, and D. T. Burke. 2002. Big mice die young: early-life body weight predicts longevity in genetically heterogeneous mice. Aging Cell 1:22 - 29. [PubMed] Harper, J. M., N. Wolf, A. T. Galecki, S. L. Pinkosky, and R. A. Miller. 2003. Hormone levels and cataract scores as sex-specific, mid-life predictors of longevity in genetically heterogeneous mice. Mech. Ageing and Development 124:801-810. [PubMed] Harper, J. M., A. T. Galecki, D. T. Burke, and R. A. Miller. 2004. Body weight, hormones and T-cell subsets as predictors of lifespan in genetically heterogeneous mice. Mechanisms of Ageing and Development 125:381-390. [PubMed] Jackson, A. U., A. Fornés, A. Galecki, R. A. Miller, and D. T. Burke. 1999. Multiple trait QTL analysis using a large mouse sibship. Genetics 151:785-795. [PubMed] [Review] Miller, R. A. 1999. Kleemeier Award Lecture: Are There Genes for Aging? J. Gerontology: Biological Sciences 54A:B297-B307. [PubMed] Jackson, A. U., A. T. Galecki, D. T. Burke, and R. A. Miller. 2003. Genetic polymorphisms in mouse genes regulating age-sensitive and age-stable T cell subsets. Genes and Immunity 4:30-39. [PubMed] Volkman, S. K. A.T. Galecki, D. T. Burke, M. R. Paczas, M. R. Moalli, R. A. Miller, and S. A. Goldstein. 2003. Quantitative trait loci for femoral size and shape in a genetically heterogeneous mouse population. Journal of Bone and Mineral Research 18:1497 -1505. [PubMed] Harper, J. M., A. T. Galecki, D. T. Burke, S. L. Pinkosky, and R. A. Miller. 2003. Quantitative trait loci for insulin-like growth factor-I, leptin, thyroxine, and corticosterone in genetically heterogeneous mice. Physiological Genomics 15:44-51. [PubMed] Volkman, S. K., A. T. Galecki, D. T. Burke, R. A. Miller, and S. A. Goldstein. 2004. Quantitative trait loci that modulate femoral mechanical properties in a genetically heterogeneous mouse population. J. Bone and Mineral Research 19:1497 - 1505. [PubMed] Wolf, N., A. Galecki, R. Lipman, S. Chen, M. Smith-Wheelock, D. Burke, and R. Miller. 2004. Quantitative trait locus mapping for age-related cataract severity and synechia prevalence using four-way cross mice. Invest. Ophthalmology and Visual Science 45:1922-1929. [PubMed] Wisser, K. C., J. A. Schauerte, D. T. Burke, A. Galecki, S. Chen, R. A. Miller, and A. Gafni. 2004. Mapping tissue-specific genes correlated with age-dependent changes in protein stability and function. Archives of Biochemistry and Biophysics 432:58-70. [PubMed] Lipman, R., A. Galecki, D. T. Burke and R. A. Miller. 2004. Genetic loci that influence cause of death in a heterogeneous mouse stock. J. Gerontol. Biol. Sci. 59A: 977 – 983. [PubMed] Hanlon, P., A. Lorenz, Z. Shao, J. Harper, A. T. Galecki, R. A. Miller, and D. T. Burke. 2006. Three-locus and four-locus QTL interactions influence mouse insulin-like growth factor-I. Physiological Genomics 26:46 – 54. [PubMed] Reeves, G. M., B. R. McCreadie, S. Chen, A. T. Galecki, D. T. Burke, R. A. Miller, and S. A. Goldstein. 2007. Quantitative trait loci modulate vertebral morphology and mechanical properties in a genetically heterogeneous mouse population. Bone 40:433-443. [PubMed] Papers about gene expression screening: Dozmorov, I., A. Bartke, and R. A. Miller. 2001. Array-based expression analysis of mouse liver genes:effect of age and of the longevity mutant Prop1df. J. Gerontol. Biol. Sci., 56A: B72-B80. [PubMed] Miller, R. A., A. Galecki, and R. J. Shmookler-Reis. 2001. Interpretation, design and analysis of gene array expression experiments. J. Gerontol. Biol. Sci. 56A: B52-B57. [PubMed] Miller, R. A., A. Galecki, and R. J. Shmookler-Reis. 2001. Letter to the editor on "Interpretation, Design, and Analysis of Gene Array Expression Experiments." J. Gerontol. Biol. Sci. 56A:B329 – B330. Dozmorov, I., A. Galecki, Y. Chang, R. Krzesicki, M. Vergara and R. A. Miller. 2002. Gene expression profile of long-lived Snell dwarf mice. J. Gerontol. Biol. Sci., 57A:B99-B108. [PubMed] Miller, R. A., Y. Chang, A. T. Galecki, K. Al-Regaiey, J. J. Kopchick, and A. Bartke. 2002. Gene expression patterns in calorically restricted mice: partial overlap with long-lived mutant mice. Molecular Endocrinology 16:2657 - 2666. [PubMed] |
