Title
Page Ligand Binding
Domain MR
Model Brookhaven
Structures Final
Thought
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Egea, P.F. Klaholz, B.P. & Moras, D. Ligand-protein interactions in nuclear receptors of hormones, FEBS Letters, Volume 476, Issues 1-2, 30 June 2000, 62-67.
Fransoijs C.J.J.; Klomp J.P.G.; & Knegtel R.M.A. Sequence annotation of nuclear receptor ligand-binding domains by automated homology modeling, Protein Engineering, Volume 13, Issue 6, 2000, 391-394.
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Klaholz B.P.; Mitschler A.; & Moras D. Structural basis for isotype selectivity of the human retinoic acid nuclear receptor, Journal of Molecular Biology, Volume 302, Issue 1, 8 September 2000, 155-170.
Kumar, R. & Thompson, B. The structure of the nuclear hormone receptors, Steroids, Volume 64, Issue 5, May, 1999, 310-319.
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Poujol N.; Wurtz J.-M.; Tahiri B.; Lumbroso S.; Nicolas J.C.; Moras D.; & Sultan C. Specific recognition of androgens by their nuclear receptor: A structure-function study, Journal of Biological Chemistry, Volume 275, Issue 31, 4 August 2000, 24022-24031.
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Wurtz, J-M. & Gronemeyer, H. . A canonical structure for the ligand-binding domain of nuclear receptors, Nature Structural Biology, Volume 3, Issue 1, January,1996, 87-94. (Figure Correction, February, 1996, 206).
Bourguet, W. Ruff, M. Chambon, P. Gronemeyer, H. & Moras, D.. Crystal structure of the ligand-binding domain of human nuclear receptor RXR-alpha, Nature, Volume 375, 1 June, 1995, 377-382.
Brzozowksi, A.M. Pike, A.C. Dauter, Z. Hubbard, R. Bonn, T. Ennstrom, O. Ohman, L. Greene, G. Gustafasson, J-A, . & Calquist, M. Molecular basis of agonism and antagonism in the oestrogen receptor, Nature, Volume 389, 16 October, 1997, 753-758.
Fagart, J. Wurtz, J-M, Souque, A. Hellal-Levy, C. Moras, D. & Raffestin-Oblin, M-E. Antagonism in the human mineralocorticoid receptor, The EMBO Journal, Volume 17, Issue 12, 1998, 3317-3325.
Renaud, J-P. Rochel, N. Ruff, M. Vivat, V. Chambon, P. Gronemeyer, H. & Moras, D.. Crystal structure of the RAR-gamma ligand-binding domain bound to the all-trans retinoic acid, Nature, Volume 378,14 December, 1995, 681689.
Williams, S.P. & Sigler, P.B. Atomic structure of progesterone complexed with its receptor, Nature, Volume 393, 28 May, 1998, 392-396.
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Wurtz,
J-M. & Gronemeyer, H. Three-Dimensional
Models of Estrogen Receptor Ligand-Binding Domain Complexes, Based on Related
Crystal Structures and Mutational and Structure-Activity Relationship Data,
Journal of Medicinal Chemistry, , Volume 41 1998,
1803-1914.
Title Page
Ligand Binding Domain
MR Model
Brookhaven Structures
Final Thought