Fibroblast Growth Factors

&

Their Receptors:

 

Site Map

by

Larry P. Taylor, Ph. D.

 

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Email: lpt

Molecular & Behavioral Neuroscience Institute

The University of Michigan

Ann Arbor, MI

 

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FGF Site: FGF Intro     Downloads     Nomenclature     Notes     References     FGF Sequences     FGFR Sequences

Information & Comparisons

Information

Backbone Comparisons

 

FGF Home

 

Kinemages

 

Nomenclature

 

Notes

 

FGF Sequences

 

FGFR Sequences

 

References

 

Gray Box Error

 

FGF

 

FGFR Ligand Binding Domain

 

FGFR 1 Tyrosine Kinase

 

SU Inhibitors-FGFR 1

 

 

Molecules Interpreted via Kinemages:

 

    FGF Molecules

 

Acidic  FGF (FGF 1)

 

FGF 1 Mutant

 

Basic  FGF (FGF 2)

 

FGF 4

 

FGF 7

 

FGF 9 (Monomer)

 

FGF 9 (Dimer)

 

FGF 12 (FHF 1)

 

FGF 19

    FGF Bound To Receptors

 

FGF   1-FGFR 1c  (Dimer)

 

FGF   1-FGFR 2c

 

FGF   1-FGFR 3c

 

FGF   2-FGFR 1c  (Dimer)

 

FGF   2-FGFR 2c

 

FGF   1-FGFR 2c-Heparin (2:2:1)

 

FGF   2-FGFR 1c-Heparin (2:2:2)

 

FGF 10-FGFR 2b

 Bound Inhibitors

 

NTS-FGF 1

 

PD-173074-FGFR 1

 

SU-4984-FGFR 1

 

SU-5402-FGFR 1

 

 

 Others

 

"Acid Box"

 

Heparin

Kinemage Downloads:

Name

 Size Description
1AXM 

2.88 M

                     FGF   1  (Acidic)

1DZC

1.25 M

                     FGF   1  Mutant
1BFF

1.30 M

                     FGF   2  (Basic)
1IJT

1.25 M

                     FGF   4
1QQK

1.43 M

                     FGF   7
1IHK

1.69 M

                     FGF   9

1G82

4.10 M

                     FGF   9 (Dimer)

1Q1U

0.904 M

                     FGF 12
1PWA

0.927 M

                     FGF 19
FgfComp 

1.529 M

       FGF 1,4,7,8b,9,10,12,19 On FGF 2
1EVT

5.13 M

       FGF   1-FGFR 1c  Dimer
1DJS

3.13 M

       FGF   1-FGFR 2c
1E0O

9.06 M

       FGF   1-FGFR 2c-Heparin  (2:2:1)
1RY7

2,99 M

       FGF   1-FGFR 3c
1CVS

8.10 M

       FGF   2-FGFR 1c Dimer
1FQ9

13.34 M

       FGF   2-FGFR 1c-Heparin  (2:2:2)
1EV2

2.39 M

       FGF   2-FGFR 2c

1NUN

3.79 M

       FGF 10-FGFR 2b
LBD

7.93 M

       FGFR Ligand Binding Domain
1RML

0.837 M

                  NTS - FGF 1
2FGI

1.12 M

       PD-173074 - FGFR 1
1AGW

1.51 M

           SU-4984 - FGFR 1
1FGI

2.16 M

           SU-5402 - FGFR 1

Inhib

1.58 M

         SU Inhibitors -FGFR 1

TyrKin

2.23 M

       FGFR 1 Tyr Kinase Domain
Box

46 K

           FGFR 2 "Acid Box"
Heparin

19 K

                     Heparin

Nom

1.88 M

       FGF/FGFR beta Sheet Nomenclature

FGF_Kin

18.72 M

       Zipped  Archive: All of the above

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FGF Site: FGF Intro     Downloads     Nomenclature     Notes     References     FGF Sequences     FGFR Sequences

My University Home     Harris Links     Chemistry / Modeling Links

Copyright 2005-2007 by Larry P. Taylor
Molecular & Behavioral Neuroscience Institute
The University of Michigan

All Rights Reserved

Supported by the Pritzker Neuropsychiatric Disorders Research Consortium, and by NIH Grant 5 P01 MH42251, Conte Center Grant #L99MH60398, RO1 DA13386 and the Office of Naval Research (ONR) N00014-02-1-0879 to Huda Akil & Stanley J. Watson. at the Molecular & Behavioral Neuroscience Institute.