Fibroblast Growth Factors

&

Their Receptors:

 

Kinemage Downloads

by

Larry P. Taylor, Ph. D. (retired)

 

Feedback appreciated; please send comments to:

Email: lpt

Molecular & Behavioral Neuroscience Institute

The University of Michigan

Ann Arbor, MI

 

This site is best viewed with

a screen resolution of 1280 x 1024.

Fibroblast Growth Factors & Their Receptors

My University Home   Harris Links     Chemistry / Modeling Links

 

FGF Site: FGF Intro     Nomenclature     Notes      References     FGF Sequences     FGFR Sequences 

Kinemages:

Kinemages (Kinetic Images) are used in protein structure classes, web sites, and journal articles for emphasizing certain aspects of protein structure. The Kinemage Home Page provides applications, utilities, databases, kinemage collections and tutorials for this protein structure rendering tool. 

MAGE (software for rendering kinemages) is available for most platforms. Since the kinemage format is widely used, hundreds of  kinemages can be found on the web. MAGE is also available as  a java application, KiNG  (Kinemages Next Generation). These applications can be downloaded from Kinemage downloads. 

In case the Richardson Kinemage site is down, the Windows executable, MAGE, and the Java executable,  KiNG, and the KiNG Manual (pdf) are available from this site.

The KiNG java application, as a default security setting,  prohibits download of the kinemage files used to render the molecules. So, for those interested  in obtaining the kinemages from this web site, the links below should start a download dialogue. If the download dialogue does not start and the file is rendered in the browser as text (first line @text), then the browser is rendering the file as text, rather than downloading the file. In this case, right click on the appropriate download link below and select the "save target as" option.  (The file should be saved in the format xxxx.kin).

To facilitate on-line browsing, the discussion  for each particular FGF species was designed with multiple KiNG applets. The downloads below contain all the individual applets for a particular molecule merged into a single kinemage package.

These kinemages were prepared on a 22" monitor operating at 1280 x 1024 resolution. Smaller screens and lower resolutions may have difficulty visualizing within MAGE all of the menu items in the more extensive kinemages (1CVS, 1E0O, 1EV2, 1EVT,  1G82, and 1NUN; 1FQ9 has far too many menu items for MAGE). If this is the case, try KiNG  (requires Java Runtime Environment) since it has a scrollable menu option to compensate for numerous right pane menu items.

The real-time visualization using KiNG of the structures on this site requires a java-enabled (JRE from Java) browser. 

 

Many browsers have disabled Java (to protect users). The files below can be downloaded and run on local machines that have installed the Java runtimes.

 

Downloads

Name

 Size Description
1AXM 

2.88 M

                     FGF   1  (Acidic)

1DZC

1.25 M

                     FGF   1  Mutant
1BFF

1.30 M

                     FGF   2  (Basic)
1IJT

1.25 M

                     FGF   4
1QQK

1.43 M

                     FGF   7
1IHK

1.69 M

                     FGF   9

1G82

4.10 M

                     FGF   9 (Dimer)

1Q1U

0.904 M

                     FGF 12
1PWA

0.927 M

                     FGF 19
FgfComp 

1.529 M

       FGF 1,4,7,8b,9,10,12,19 On FGF 2
1EVT

5.13 M

       FGF   1-FGFR 1c  Dimer
1DJS

3.13 M

       FGF   1-FGFR 2c
1E0O

9.06 M

       FGF   1-FGFR 2c-Heparin  (2:2:1)
1RY7

2,99 M

       FGF   1-FGFR 3c
1CVS

8.10 M

       FGF   2-FGFR 1c Dimer
1FQ9

13.34 M

       FGF   2-FGFR 1c-Heparin  (2:2:2)
1EV2

2.39 M

       FGF   2-FGFR 2c

1NUN

3.79 M

       FGF 10-FGFR 2b
LBD

7.93 M

       FGFR Ligand Binding Domain
1RML

0.837 M

                  NTS - FGF 1
2FGI

1.12 M

       PD-173074 - FGFR 1
1AGW

1.51 M

           SU-4984 - FGFR 1
1FGI

2.16 M

           SU-5402 - FGFR 1

Inhib

1.58 M

         SU Inhibitors -FGFR 1

TyrKin

2.23 M

       FGFR 1 Tyr Kinase Domain
Box

46 K

           FGFR 2 "Acid Box"
Heparin

19 K

                     Heparin

Nom

1.88 M

       FGF/FGFR beta Sheet Nomenclature

FGF_Kin

18.72 M

       Zipped  Archive: All of the above

 

KiNG Manual 

100 K

               King Manual (pdf)

 

According to the University of Michigan Web Log:

 

Total Downloads since August, 2005: 214, 762  (Last counter update: 8 / 01 / 2018)
Downloads during the last calendar month:  269
Maximum Monthly Downloads: 5719

Top

My University Home   Harris Links     Chemistry / Modeling Links

 

FGF Site: FGF Intro     Nomenclature     Notes      References     FGF Sequences     FGFR Sequences 

Copyright 2005-2020 by Larry P. Taylor
Molecular & Behavioral Neuroscience Institute
The University of Michigan

All Rights Reserved

Supported by the Pritzker Neuropsychiatric Disorders Research Consortium, and by NIH Grant 5 P01 MH42251, Conte Center Grant #L99MH60398, RO1 DA13386 and the Office of Naval Research (ONR) N00014-02-1-0879 to Huda Akil & Stanley J. Watson. at the Molecular & Behavioral Neuroscience Institute.