Hello, my name is Patrick Langechuan Liu, and I currently work as a detector physicist at the Medical Imaging division of PerkinElmer Inc. I received my PhD with distinction in Physics at the University of Michigan in Ann Arbor.

Trained as a physicist, I have developed strong analytical skills and a particular interest in imaging science. I have constantly found that the most enjoyable part of my job involves gaining useful insights through mining large sets of data.



2008 - 2014 Ann Arbor, MI

University of Michigan

Physics, PhD (with Distinction) // GPA: 4.0/4.0

• Department of Physics, Rackham Graduate School

• Department of Radiation Oncology - Physics Division

2004 - 2008 Beijing, China

Peking University

Physics, BSc // GPA: 3.7/4.0

• Department of Physics, School of Physics

• Center for Theoretical Biology


Megavoltage Imager

Thesis Project

>>Details

Ultrasound Calligraphy

Medical Imaging

>>Details

NHK Documentary

Translation

>>Details

Speech Contest

Public Speaking

>>Details

Velocyk

Entrepreneurship

T-shirt Design

Graphic Design


2015 - Present Santa Clara, CA

Detector Physicist

PerkinElmer Medical Imaging

• Performed design and test various amorphous silicon and CMOS detectors for X-ray imaging

• Optimized detector test procedures and cut testing time by 60% through analysis of 5 years of test data (60 TB+ image and text files stored on in-house server) in Python

• Reduced time for defect analysis from 5 minutes to 3 seconds (100x speedup) by developing new algorithms

• Developed a GUI to analyze test images and identify detectors of passing grade using logistic regression

• Increased X-ray detector spatial resolution by 80%+ by adopting a barrier rib structure in the scintillator layer

2015 - Present Santa Clara, CA

Data Science Fellow

The Data Incubator

• Selected as one of 30 fellows from 1800 applicants to participate in an intensive data science fellowship program

• Performed sentiment analysis through construction of bag-of-words and bigram models based on more than 1 million Yelp reviews using Scikit-learn library in Python

• Predicted business star-rating through linear regression of the features extracted from 30,000+ Yelp records

• Identified the most common restaurant violations in different cuisine types based on analysis of more than 500,000 restaurant inspection records in New York City using SQL

• Constructed and analyzed a social network of celebrities in NYC using data scraped from 1200+ webpages

• Revealed relationships among Wikipedia pages by analyzing the network of links on all English Wikipedia pages (10 GB+ of HTML files stored on Amazon Web Service) using MapReduce algorithms in mrjob framework

2009 - 2014 Ann Arbor, MI

Research Assistant

Department of Radiation Oncology
University of Michigan

• Pioneered design optimization of megavoltage X-ray detectors for radiotherapy portal imaging and MV CBCT

• Designed and conducted numerical modeling through parallel Monte Carlo simulation on 800+ CPU cores

• Invented a hybrid modeling framework to reduce simulation time from 100 million down to only 30 CPU hours

• Designed and implemented CT reconstruction algorithm and imaging performance analysis in MATLAB

• Created and implemented model-based iterative reconstruction algorithms for limited field-of-view CT imaging

• Communicated and collaborated closely with researchers and consultants across research institutes

Spring 2012 Ann Arbor, MI

Entrepreneur

Center for Entrepreneurship
University of Michigan

• Led a team of three students and coordinated teamwork on an affordable motorized commuter bike

• Conducted over 50 interviews, pivoted prototype design and business model based on customer discovery

• Established partnership with occupational education program at local community college

Spring 2012 Chicago, IL

Consultant Trainee of Bridge to BCG

Boston Consulting Group

I was selected as one of the three U of M participants for a on-site program offered by Boston Consulting Group for Advanced Degree holders

• Analyzed and created a detalied solution for a mock consulting case

• Presented the solution in front of executives and fellow participants

Summer 2011 Chicago, IL

Consultant Trainee of Insight Asia

McKinsey & Company

I was selected as one of the two U of M participants for a on-site program offered by McKinsey for Advanced Degree holders

• Obtained the problem-solving methodology in management consulting industry

• Team-worked through practices of mini-cases, group discussion and presentation

2009-2010 Internet

Volunteer Translator

Tao Orchid (Daolan) Translation Group

Daolan Translation Group is the largest and most famous non-profit documentary translation group in China (http://daolan.net/)

• Lead 7 projects to translate feature-length documentaries from Japanese to Chinese

• Bridged information gap due to language barrier and television program censorship

• Collaborated online with university professors and professional translators from all over the world

• Work highlighted by media and adopted by more than 20 universities as educational materials

2008-2009 Ann Arbor, MI

Instructor

Department of Physics
University of Michigan

• Delivered independently prepared physics lectures to over 150 university students

• Tutored Mechanics and Electromagnetism physics labs, graded lab reports and research project papers

• Received excellent reviews from students during course feedback

Summer 2008 Beijing, China

Project Manager

Comics Club T-Shirt Project
Peking University

• Initiated a customized T-shirt design contest to promote Peking University Comics Club

• Reduced cost by 50% through creation of online ordering tools and negotiation for competitive quotes

• Profited $300 from 1000+ orders, which was donated to Relief Fund for the 2008 Sichuan Earthquake


Nov 2013 Ann Arbor, MI

Rackham Travel Grant

University of Michigan

July 2011 Ann Arbor, MI

Rackham Travel Grant

University of Michigan

March 2011 Detroit, MI

1st Place in Michigan Japanese Language Speech Contest

Consulate-General of Japan in Detroit

June 2008 Beijing, China

Outstanding Graduate Student

Peking University, China

Nov 2007 Beijing, China

DTZ Scholarship

DTZ Group, Hong Kong

Nov 2006 Beijing, China

POSCO Scholarship

POSCO, South Korea

Oct 2006 Beijing, China

All-round Excellent Student

Peking University

May 2006 Beijing, China

Undergraduate Research President's Fellowship

Peking University

Otc 2005 Beijing, China

Dean's Award for Acdemic Excellence

Peking University


Peer-reviewed Publications

Theoretical investigation of the design and performance of a dual energy (kV and MV) radiotherapy imager

Langechuan Liu, Larry Antonuk, Youcef El-Mohri, Hao Jiang, Qihua Zhao, Medical Physics (Accepted, 2015)

Optimization of the design of thick, segmented scintillators for megavoltage cone-beam CT using a novel, hybrid modeling technique [Link to aip.org]

Langechuan Liu, Larry Antonuk, Youcef El-Mohri, Qihua Zhao, Hao Jiang, Medical Physics, 41, 061916 (2014)

Optimization of the performance of segmented scintillators for radiotheraoy imaging through novel binning technique [Link to iop.org], featured in MedicalPhyicsWeb

Youcef El-Mohri, Larry Antonuk, Richard Choroszucha, Qihua Zhao, Hao Jiang, Langechuan Liu, Physics in Medicine and Biology, 59 (2014) 797-818

Countering Beam Divergence Effects with Focused Segmented Scintillators for High DQE Megavoltage Active Matrix Imagers [Link to PubMed Central]

Langechuan Liu, Larry Antonuk, Qihua Zhao, Youcef El-Mohri, Hao Jiang Physics in Medicine and Biology, 57 (2012) 5343-58

Low-dose megavoltage cone-beam CT imaging using thick, segmented scintillators [Link to PubMed Central]

Youcef El-Mohri, Larry Antonuk, Qihua Zhao, Richard Choroszucha, Hao Jiang, Langechuan Liu Physics in Medicine and Biology, 56 (2011) 1509-1527

Conference Presentations

Multi-Energy Imagers for a Radiotherapy Treatment Environment

Larry Antonuk, Langechuan Liu, Albert Liang, Youcef El-Mohri, Qihua Zhao, Martin Koniczek, Hao Jiang, SPIE Medical Imaging 2015, 9412-14

Theoretical investigation of the design and performance of dual energy x-ray detectors for kV and MV CBCT imaging in a radiotherapy treatment room

Larry Antonuk, Langechuan Liu, Youcef El-Mohri, Hao Jiang, Qihua Zhao, RSNA 2014, SSJ21-06

Design Optimization of Segmented Scintillators for Megavoltage Cone-Beam CT [Link to aapm.org]

Langechuan Liu, Larry Antonuk, Youcef El-Mohri, Qihua Zhao, Hao Jiang, AAPM 2014, TH-A-18C-1

Optimization of the design of portal imaging systems incorporating thick, segmented scintillating detectors employed for megavoltage cone-beam CT through a novel hybrid modeling technique [PDF file]

Langechuan Liu, Larry Antonuk, Hao Jiang, Youcef El-Mohri, Qihua Zhao, RSNA 2013, SST15-06

Implications of Orders-of-Magnitude Improvement in DQE Performance of Conventional Electronic Portal Imagers [Link to RSNA.org]

Larry Antonuk, Youcef El-Mohri, Qihua Zhao, Langechuan Liu, Hao Jiang, RSNA 2012, LL-PHS-TH2B

Investigation of Novel, Focused, Segmented Scintillator Geometries for High DQE Megavoltage Active Matrix Imagers [Link to aip.org]

Larry Antonuk, Langechuan Liu, Qihua Zhao, Youcef El-Mohri, Hao Jiang, Robert Street AAPM 2011, Radiography/Projection Imaging Section, SU-C-220-6

Theoretical Limits to System Performance of High Efficiency, Direct Detection, Megavoltage Active Matrix Flat-Panel Imagers Based On Polycrystalline Mercuric Iodide [Link to aip.org]

Qihua Zhao, Langechuan Liu, Youcef El-Mohri, Larry Antonuk, Hao Jiang, Martin Koniczek AAPM 2010, Imaging General Section, SU-GG-I-136