Papers and Publications

• Lee, S., Teslovich, T., Boehnke, M., Lin, X. (2013). General framework for meta-analysis of rare variants in sequencing association studies. American Journal of Human Genetics, 93, 42-53.
  
• Ionita-Laza, I.*, Lee, S.*, Makarov, V., Buxbaum, J. Lin, X. (2013). Sequence kernel association tests for the combined effect of rare and common variants. American Journal of Human Genetics, 92, 841-853.
  *Joint first author.
• Lin, X., Lee, S., Christiani, D. and Lin, X. (2013). Test for interactions between a Gene/SNP-set and Environment/Treatment in generalized linear models. Biostatistics, doi: 10.1093/biostatistics/kxt006.
• Wu, M.C., Maity, A., Lee, S., Simmons, E.M., Molldrem, J.J. and Armistead, P.M. (2011) Kernel machine SNP-set testing under multiple candidate kernels. Genetic Epidemiology, , 37, 267-275.
• Ionita-Laza, I., Lee, S., Makarov, V., Buxbaum, J. Lin, X. (2012). Family-based association tests for sequence data, and comparisons with population-based association tests. European Journal of Human Genetics, doi: 10.1038/ejhg.2012.308.
• Barnett, I., Lee, S. and Lin, X. (2012). Detecting Rare Variant Effects Using Extreme Phenotype Sampling in Sequencing Association Studies. Genetic Epidemiology, 37, 142-151
• Lee, S., Emond, M.J., Bamshad, M.J., Barnes, K.C., Rieder, M.J. Nickerson, D.A., NHLBI GO Exome Sequencing ProjectESP Lung Project Team, Christiani, D.C., Wurfel, M.M. and Lin, X. (2012). Optimal unified approach for rare variant association testing with application to small sample case-control whole-exome sequencing studies. American Journal of Human Genetics, 91, 224-237.
• Lee, S., Wu, M. and Lin, X. (2012). Optimal tests for rare variant effects in sequencing association studies. Biostatistics, 13, 762-775
  Supplementary materials
• Wu, M.*, Lee, S. *, Cai, T., Li, Y., Boehnke, M. and Lin, X. (2011). Rare Variant Association Testing for Sequencing Data Using the Sequence Kernel Association Test (SKAT). American Journal of Human Genetics, 89, 82-93.
  *Joint first author.
• Lee, S., Wright, F.A. and Zou, F. (2011). Control of population stratification by correlation-selected principal components.. Biometrics, , 67, 967-974.
• Lee, S., Zou, F. and Wright, F.A. (2010). Convergence and prediction of principal component scores in high dimesional settings. Annals of Statistics, 38, 3605-3629.
• Zou, F., Lee, S., Knowles, M.R. and Wright, F.A. (2010). Quantification of Population Structure Using Correlated SNPs by Shrinkage Principal Components. Human Heredity, 70, 9-22.
• Zou, F., Huang, H., Lee, S. and Hoeschele, I. (2010). Nonparametric bayesian variable selection with applications to multiple quantitative trait loci mapping with epistasis and gene-environment interaction. Genetics, 186, 385-394.
• Lee, S., Sullivan, P.F., Zou, F. and Wright, F.A. (2008). Comment on a simple and improved correction for population stratification. American Journal of Human Genetics, 82, 524-526.

• Collaborative Cross Consortium (2011). The Genome Architecture of the Collaborative Cross Mouse Genetic Reference Population, Genetics, 190, 389-401.
• Sun, W., Lee, S. , Zhabotynsky, V., Zou, F., Wright, F.A., Crowley, J.J., Yun, Z. , Buus, R., Miller, D., Wang, J., McMillan, L., de Villena, F. and Sullivan, P.F. (2011). Transcriptome atlases of mouse brain reveals differential expression across brain regions and genetic backgrouds. G3: Genes, Genomes, Genetics , 2, 203-211.
• Wright, F.A., Strug, L.J., Doshi, V.K., Commander, C.W., Blackman, S.M., Sun, L., Berthiaume, Y., Cutler, D., Cojocaru, A., Collaco, J.M, Corey, M., Dorfman, R., Goddard, K., Green, D., Kent Jr, J.W., Ethan, Lange, Lee, S. , Li, W., Luo, J., Mayhew, G., Naughton, K., Pace, R., Paré, P., Rommens, J. Sanfrod, A., Stonebraker, J.R., Sun, W., Taylor, C., Vanscoy, L.L., Zou, F., Blangero, J., Zielenski, J., ONeal, W.K., Drumm, M.L., Durie1, P.R., Knowles, M.R., Cutting, G.R. (2011). Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. Nature Genetics, , 43, 539-546.
• Jeong, J., Choi, M. , Cho, Y., Lee, S. , Oh, J., Park, J., Cho, Y., Lee, I., Kim, S., Han, S. , Choi, K. and Chung, I. (2008). Chronic gastrointestinal symptoms and quality of life in the Korean population. World Journal of Gastroenterology, 14(41), 6388-6394.
• Sullivan, P.F., Lin, D., Tzeng, J-Y, E van den Oord,Perkins, D., Stroup, T.S., Wagner, M.,Lee, S., Wright, F.A., Zou, F., Liu, W., Downing, A.M., Lieberman, J. and Close S.L. (2008). Genomewide association for schizophrenia in the CATIE study: results of stage 1. Molecular Psychiatry, 13(6), 570-84.
• Li, W., Sun, L., Corey, M., Zou, F., Lee, S., Cojocaru, A.L., Taylor, C., Blackman, S.M., Stephenson, A., Sandford, A.J., Dorfman, R., Drumm, M.L., Cutting, G.R., Knowles, M.R., Durie, P., Wright F.A., and Strug L.J. (2011). Understanding the population structure of North American patients with cystic fibrosis. Clinical Genetics, 79, 136-46.

• Lee, S., Zou, F. and Wright, F.A. (2013). Convergence of sample eigenvalues, eigenvectors and PC scores for ultra-high dimensional data. under review