Developing new Treatments for Tourette Syndrome: Therapeutic Trials with Modulators of Glutamatergic Neurotransmission

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This research is being done to determine whether glutamate altering drugs are effective at suppressing tics.  Included in this double-blind, placebo-controlled 8 week study are both a glutamate agonist (D-serine) and riluzole (a glutamate antagonist). This study is approved by the FDA and the Johns Hopkins IRB.  Individuals aged 8-17 years with moderate to moderate-severe Tourette syndrome or chronic motor/vocal tics (total tic score >22) may join. Participants would need to be available come to Baltimore every two weeks for eight weeks.

Handout for doctors

Handout for patients

Research Assistant: Christy Morris-Berry

This study is approved by the Johns Hopkins Institutional Review Board (NA_ 00023969).

Sponsored by the NIH.


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Last revised 11-Feb-2011 by Steven Leber