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Jeffrey Sean Huo MD PhD
e-mail (primary): jeffshuo@umich.edu
e-mail (alternate/permanent): jeffreyshuo@gmail.com
Current Work
Research and Professional Interests
Education
Board Certification
General Pediatrics, American Board of Pediatrics, 2011
Pediatric Hematology/Oncology, American Board of Pediatrics, 2015
Publications
- Roca, H. Pande, M. Huo, JS. Hernandez, J. Cavalcoli, JD.
Pienta, KJ. McEachin, RC. A bioinformatics approach reveals novel
interactions of the OVOL transcription factors in the regulation of
epithelial - mesenchymal cell reprogramming and cancer progression. BMC
Systems Biology. In press.
- Park, TS. Bhutto, I. Zimmerlin, L. Huo, JS. Nagaria P. Miller,
D. Rufaihah, AJ. Talbot, C. Aguilar, J. Grebe, R. Merges, C. Reijo-Pera,
R. Feldman, RA. Rassool, F. Cooke, J. Lutty, G. Zambidis, ET. Vascular
Progenitors from Cord Blood-Derived iPSC Possess Augmented Capacity for
Regenerating Ischemic Retinal Vasculature. Circulation. 129(3):359-72.
2014. PMCID
24163065.
- Huo, JS. Zambidis, ET. Pivots of pluripotency: The roles of
non-coding RNA in regulating embryonic and induced pluripotent stem cells.
Biochimica Biophysica Acta. 1830(2):2385-94. 2013. PMCID
23104383.
- Park, TS. Huo, JS. Peters, A. Talbot, CC. Verma, K. Zimmerlin,
L. Kaplan, IM. Zambidis, ET. Growth factor-activated stem cell circuits
and stromal signals cooperatively accelerate non-integrated iPSC
reprogramming of human myeloid progenitors. PLoS One. 7(8):e42838. 2012.
PMCID
22905176.
- Kurachi, S. Huo, JS. Ameri, A. Zhang, K. Yoshizawa, A. Kurachi,
K. An age-related homeostasis mechanism is essential spontaneous
amelioration of hemophilia B Leyden. Proc Natl Acad Sci U S A.
106(19):7921-6. 2009. PMCID
19416882.
- Chen Y, Lin G, Huo, JS. Barney D, Wang Z, Livshiz T, States
DJ, Qin ZS, Schwartz J. Computational and functional analysis of growth
hormone-regulated genes identifies the transcriptional repressor Bcl6 as a
participant in GH-regulated transcription. Endocrinology. 150(8):3645-54.
2009. PMCID
19406940.
- Watkins, MG. Dejkhamron, P. Huo, J. Vazquez, DM. Menon, RK.
Persistent neonatal thyrotoxicosis in a neonate secondary to a rare
thyroid-stimulating hormone receptor activating mutation: case report and
literature review. Endocr Pract. 14(4): 479-83. 2008. PMCID
18558604.
- Chen, L. Maures, TJ. Jin, H. Huo, JS. Rabbani, SA. Schwartz, J.
Carter-Su, C. SH2B1beta (SH2-Bbeta) enhances expression of a subset of
nerve growth factor-regulated genes important for neuronal differentiation
including genes encoding urokinase plasminogen activator receptor and
matrix metalloproteinase 3/10. Mol Endocrinol. 22(2): 454-76. 2008. PMCID
17947375.
- Huo, JS. McEachin, RC. Duggal, NK. Hai, T. States, DJ.
Schwartz, J. Profiles of Growth Hormone-Regulated Genes Identify a Role
for C/EBPb in Expression of ATF3. J. Biological Chemistry 281: 4132-4141,
2006. PMCID
16326703.
- Cui, TX. Piwien-Pilipuk, G. Huo, JS. Kaplani, JI. Kwok R.
Schwartz, J. Endogenous C/EBPb and p300 are Dynamically Regulated by
Growth Hormone. Mol. Endocrinol. 19:2175-86. 2005. PMCID
15860545.
- Schwartz, J. Huo, JS. Piwien-Pilipuk,
G. Growth Hormone Regulated Gene Expression. Minerva Endocrinol. 4:231-41. 2002.
- Kurachi, K. Zhang, K. Huo, J. Ameri, A. Kuwahara, M. Fontaine, JM.
Yamamoto, K. Kurachi, S. Age-related
Regulation of Genes: Slow Homeostatic Changes and Age-Dimension
Technology. Physica A. 315:1-5-113. 2002.
- Piwien-Pilipuk, G. Huo, JS. Schwartz, J. Growth Hormone Signal
Transduction. J. Pediatric Endocrinology Metabolism 15:771-86. 2002.
- Kurachi, S. Ameri, A. Huo, J. Hoff, J. Atoda, H. Kurachi, K.
Specific gene expression switches are responsible for puberty-onset
amelioration of transgenic mouse Leyden: construction of transgenic mouse
models and role of growth hormone. Blood 96: (11) 2107, Part 1. 2000.
(Abstract)
- Kurachi, K. Zhang KZ. Ameri, A. Huo, J. Atoda, H. Kurachi, S. IUBUMB
Life 49(3):189-196.
- Kurachi, S. Ameri, A. Huo, J. Pantazatos, D. Hoff, J. Kurachi, K.
Blood 94(10):455A Part 1. Suppl 1.
- Acknowledgment in Kurachi, S. Deyashiki, Y. Takeshita, L.
Kurachi, K. Science 285(5428):739-743.
Fellowships and Scholarships (selected)
Honors and Awards
(selected)
- NIH Pediatric Oncology Branch Research Day - Poster Award (4 / 40+
presenters), 2013
- U. Michigan Medical Center Alumni Society 3rd Year Student Service
Award ( 1 / class), 2006
- U. Michigan Cardiovascular Research Symposium Poster Award (2 / 20+ presenters), 2000
- Departmental Honors (Biomedical Engineering), 1997
- Tau Beta Pi National Engineering Honor Society, 1997
- Mortar Board National Honor Society, 1996
- Golden Key National Honor Society, 1996
- Dean's List, Northwestern University (6/9 quarters, one with high honors)
Personal Information
May 12th, 2015
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