Research Interests/Projects

	Modeling of GPCRs by distance geometry algorithm
	Homology modeling of protein structure
	Ligand docking
	Knowledge-based drug design
	Peptide synthesis
	EPR-spectroscopy, absorption spectroscopy

Finger information

Always stand at the edge

1. Pogozheva I.D., Lomize A.L. and Mosberg H.I. The transmembrane 7-a-bundle of rhodopsin: distance geometry calculations with hydrogen bonding constraints. Biophysical Journal. 72(5):1963-1985, 1997. Abstract.
2. Mosberg H.I., Dua R.K., Pogozheva I.D. and Lomize A.L. Development of a model for the d-opioid receptor pharmacophore. 4. Residue 3 dehydrophenylalanine analogues of Tyr-c[D-Cys-Phe-D-Pen]OH (JOM-13) confirm required gauche orientation of aromatic side chain. Biopolymers. 39(3):287-296, 1996. Abstract.
3. Lomize A.L., Pogozheva I.D. and Mosberg H.I. Development of a model for the d-opioid receptor pharmacophore: 3. Comparison of the cyclic tetrapeptide, Tyr-c[D-Cys-Phe-D-Pen]OH with other conformationally constrained d-receptor selective ligands. Biopolymers. 38(2):221-234, 1996.Abstract.
4. Pogozheva I.D., Lomize A.L. and Mosberg H.I. The origin of specificity in the opioid receptor family. Peptides: Chemistry, Structure, and Biology, Proceedings of the 15^th American Peptide Symposium, in press 1998. Abstract.
5. Pogozheva I.D., Lomize A.L. and Mosberg H.I. Opioid receptor 3D structures from distance geometry calculations with hydrogen bonding constraints.Biophysical Journal submitted 1998. Abstract.
6. Lomize A.L, Pogozheva I.D. and Mosberg H.I. Structural organization of G protein-coupled receptors.Perspectives in Drug Discovery and Design, in press, 1998. Abstract.

1. Kalamkarov G., Pogozheva I., Shevchenko T., Koskelainen A., Hemila S. and Donner K .  pH changes in frog rods upon manipulation of putative pH-regulating transport mechanisms. Vision Research. 36(19):3029-36, 1996. Abstract
2. Kalamkarov G.R., Shevchenko T.F. and Pogozheva I.D. Te role of HCO3-/Cl- exchange in the regulation of phototransduction in the retinal cell.  Biologicheskie membrani (USSR), 8: 1195-1197, 1991. 
3. Pogozheva I.D., Shevchenko T.F., Livshits V.A. and Kalamkarov G.R. Determination of transducin binding sites by local rhodopsin SH-group modification. Biologicheskie membrani (USSR), 8: 44-49, 1991. Abstract.
4. Donner K., Hemila S., Kalamkarov G., Koskelainen A., Pogozheva I. and Rebrik T. Sulfhydryl binding reagents increase the conductivity of the light-sensitive channel and inhibit phototransduction in retinal rods. Experimental Eye Research. 51(1):97-105, 1990. Abstract
5. Pogozheva I.D., Shevchenko T., Livshits V.A. and Kalamkarov G.R. Influence of sylfhydryl group modification on arrestin interaction with phosphorylated rhodopsin. Biologicheskie membrani (USSR), 6: 1248-1255, 1989. Abstract.
6. Pogozheva I.D., Shevchenko T., Livshits V.A. and Kalamkarov G.R. Interaction of rhodopsin and arrestin:the role of rhodopsin phosphorylation.  Biologicheskie membrani (USSR), 6: 1237-1247, 1989. Abstract.
7. Pogozheva I.D., Kuznetsov V.A., Fedorovich I.B. and Ostrovskii M.A. ESR Saturation transfer study of photoinduced changes in the hydrophilic regions of rhodopsin. Biologicheskie membrani (USSR), 2: 880-896, 1985. Abstract.
8. Pogozheva I.D., Kuznetsov V.A., Fedorovich I.B. and Ostrovskii M.A. Conformational mobility and interactions of rhodopsin domains. Biologicheskie membrani (USSR), 2: 897-905, 1985. Abstract.
9. Pogozheva I.D., Kuznetsov V.A., Livshits V.A. and Kuznetsov A.N. Influence of a magnetic field on the aggregation of rhodopsin molecules during photooxidation of photoreceptor membranes. Biofizika (USSR). 28(2):336-7, 1983.
10. Pogozheva I.D., Kuznetsov V.A., Fedorovich I.B., Livshits V.A., Ostrovskii MA. Manoshkina N.B. Aggregation of rhodopsin molecules during damaging exposure of photoreceptor membranes to light. Biofizika (USSR). 26(4):692-700, 1981. Abstract
11. Pogozheva I.D., Fedorovich I.B., Ostrovskii M.A. and Emanuel' N.M. Photodamage of rhodopsin molecule. Oxidation of SH-group. Biofizika.(USSR). 26(3):398-403, 1981. Abstract
12. Pogozheva I.D., Kuznetsov V.A., Livshits V.A., Fedorovich I.B. and Ostrovskii MA. Reversible pH-dependent aggregation of rhodopsin molecules in photoreceptor membranes. Doklady Akademii Nauk SSSR (USSR).  260(5):1254-8, 1981. Abstract.