Mar. 4

What is Pharmacogenomics?

(HW Read 251-272 of course reader)

Mar. 6

Genetics and Molecular Biology in Medicine

(HW Read pg 1-51 of course reader)

Assignment 1

Mar. 11

Assignment 1 due at beginning of class

Genetics and Molecular Biology in Medicine

(HW Read pg 1-51 of course reader)

Mar. 13

How PGx improves drug toxicity and efficacy

(HW Read pg 273-336 of course reader)

Assignment 2

Mar. 18

Assignment 2 due at beginning of class

What are the Mechanisms Behind This Variability?

 (HW Read pg 337-376 of course reader)

Mar. 20

How Genetic Tests Can Predict Efficacy and Toxicity?

(HW Read pg 377-399 of course reader)

HW Assignment 3

Mar. 25

Pharmacogenomics and the future of pharmaceuticals

Mar. 27

Assignment 3 due at beginning of class

Review

Apr. 1

Exam I

Apr. 3

Race and Pharmacogenomics

(HW Read pg 225-250 and 401-442 of course reader)

Assignment 4

Apr. 8

Assignment 4 due at beginning of class

Legal, Social and Ethical Aspects of Genetic Testing

HW: Read warfarin NEJM article)

Apr. 10

Pharmacogenomics Case Study I: Personalized anticoagulant therapy

(Read  abacavir NEJM article.)

Apr. 15

Assignment 5 due at beginning of class

Pharmacogenomics Case Study II: Drug Hypersensitivity

April 17

Review and Take home Exam 2 (due April 20^th at noon, 3062 Pharm)