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Cell-cell interactions during fertilization in Arabidopsis : the role of the pollen coat.
Jacob Mayfield, Lisa DuPree, Samantha Chau, Daphne Preuss
Department of Molecular Genetics and Cell Biology, University of Chicago, EBC 404, 1103 E. 57th Street, Chicago, IL 60637 [presenter's e-mail: jamayfie@midway.uchicago.edu]

Because plants rely on fortuitous processes to distribute pollen, they must distinguish pathogens and foreign pollen from gametes of their own species. The first step in a series of cell-cell interactions begins at the stigma, where dehydrated, mature pollen is hydrated and allowed to grow only if compatible. Identification of sterile mutations in Arabidopsis thaliana and simultaneous investigation of the pollen coating composition have advanced the understanding of pollen-pistil communication at the molecular level. The extracellular matrix of pollen consists of long-chain lipids and lipophilic proteins. We have characterized a male-sterile mutation (cer6-2) that lacks an extracellular pollen coating, affecting fertilization at the initial step. Instead of allowing pollen hydration and germination, stigma cells undergo a defense response. Because cer6-2 sterility can be reversed by hydrating mutant pollen in a humid chamber, we have been able to obtain suppressing mutations. Addition of wild-type pollen coat extract to cer6-2 pollen rescues fertility, implicating the coating as the source of critical signaling components. We have purified three of the major pollen coat proteins and are investigating their role in fertilization. The pollen composition of many races of Arabidopsis manifest striking differences, hinting at a mechanism for rapid speciation. Differences in the pollen coat components have allowed genetic mapping of the variations to a single region. Molecular cloning of purified pollen proteins and studies to correlate variations of the pollen coat with fertilization efficiency are currently in progress. These studies provide insight into pollen-pistil communication and cell-cell interaction.