We are interested in animal behavior and neuronal physiology and we focus on using novel technologies and nano-tools in order to investigate intracellular mechanisms. The dynamics of intracellular systems is in the core of this research and we combine biochemistry and molecular biology methods with engineering techniques and computational and modeling tools.

Complex Bio-Nano-Dynamics of Axonal Transport

We are studying kinesin-mediated axonal transport. We combine cell biology techniques, microfluidics and modeling to study obstructions and delays in motor protein motion. We aim to connect our findings with observations from neurodegenerative diseases.

This project focuses on modeling artificial neuronal networks and investigate the parameters which affect their performance and connectivity. Using cultured neurons, we are also running experiments to establish a cross talk between the two approaches.

 

 

Changes in a neuronal network activity by altering maximum conductance and rise time
(generated by Ehsan Mizrakhalili)

Magnetic Field Effects on Model Organisms Locomotion Control and Mechanics

Our research includes experiments with the C. elegans nematode exposed to magnetic field, after being fed with magnetic nanoparticles. We also model the interaction between magnetic field and ingested particles. We are interested in both the magnetic and the mechanical forces affecting intracellular structures and overall animal behavior.