University of Michigan
Dept of Biostatistics
1415 Washington Hts, Ann Arbor, MI, 48104
Email: cristen at umich dot edu
I'm an Assistant Professor in the Division of Cardiovascular Medicine and Department of Human Genetics at the University of Michigan. I'm interested in studying complex genetic diseases, particularly the genetics of quantitative traits such as lipid levels and human obesity. I've also been recently working on imputation of ungenotyped markers, population genetics, bioinformatics, and understanding the function behind genetic associations.
Recently we developed an online tool, LocusZoom, for plotting association results at a regional level.
Feb 2004 to present: Postdoctoral Research Associate
Department of Biostatistics, University of Michigan
Advisor: Michael Boehnke, Finland-United States Investigation of NIDDM Genetics (FUSION)
Project: Identification of genes associated with T2D-related quantitative traits such as lipid levels, body mass index and blood pressure. Performing genome-wide association scans, meta-analysis within large consortia, selection of top results for follow-up and interpreting the biological importance of associated genome regions.
Aug 2003: D. Phil. (Ph.D.)
University of Oxford, Oxford, UK
Thesis title: Genetic and environmental susceptibility to multiple sclerosis
Advisor: Prof. George C. Ebers, Canadian Collaborative Project on Genetic Susceptibility to MS
Jun 1998: B. Sc. (Hons)
McMaster University, Hamilton, Canada
Molecular Biology and Biotechnology (summa cum laude)
K99/R00 Pathway to Independence Award, Sept 2009 - Aug 2014
American Diabetes Association Postdoctoral Fellowship, Sept 2006 - Aug 2009
Multiple Sclerosis Society of Canada PhD Studentship, Sept 2001 - July 2003
Canada Scholar, Ontario Scholar, 2004
Note (* indicates equal contribution)
44. Li Y, Willer CJ, Ding J, Scheet P, Abecasis GR. MaCH: Using sequence and genotype data to estimate haplotypes and unobserved genotypes. (In Press at Genetic Epidemiology)
43. Speliotes EK*, Willer CJ*, Berndt SI*, Monda KL*, Thorleifsson G*, Jackson AU, Lango Allen H, Lindgren CM, Luan J, Magi R, Randall JC, Vedantam S, [plus 351 additional authors], Wichmann H-E, Frayling TM, Thorsteinsdottir U, Abecasis GR, Barroso I, Boehnke M*, Stefansson K*, North KE*, McCarthy MI*, Hirschhorn JN*, Ingelsson E*, Loos RJF*. Association analyses of 249,746 individuals reveal eighteen new loci associated with body mass index (In Press at Nature Genetics)
42. Lango Allen H*, Estrada K*, Lettre G*, Berndt SI*, Weedon MN*, Rivadeneira F*, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, [plus 269 additional authors], Uitterlinden A, Visscher P, Chatterjee N, Loos RJF, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Abecasis GR*, Stefansson K*, Frayling T*, Hirschhorn JN*. Hundreds of variants influence human height and cluster within genomic loci and biological pathways (In Press at Nature)
41. Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Zillikens MC, Speliotes EK, Magi R, Workalemahu T, White CC, Bouatia-Naji N, Harris TB, Berndt SI, Ingelsson E, Willer CJ, Weedon MN, [plus 268 additional authors], Assimes TL, Wichmann H-E, Thorsteinsdottir U, van Duijn CM, Stefansson K, Cupples LA, Loos RJF, Barroso I, McCarthy MI, Fox CS, Mohlke KL, Lindgren CM. Meta-analysis identifies 13 novel loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. (In Press at Nature Genetics)
40. Pruim RJ*, Welch RP*, Sanna S, Teslovich TM, Chines PS, Gliedt TP, Boehnke M, Abecasis GR, Willer CJ. (2010) LocusZoom: Regional visualization of genome-wide association scan results. Bioinformatics PMID: 20634204
39. Willer CJ, Li Y, Abecasis GR. (2010) METAL: Fast and efficient meta-analysis of genomewide association scans. Bioinformatics PMID: 20616382
38. Teslovich TM, Musunuru K, Smith AV, Edmondson A, Sylianou IM, Koseki M, Rapatti S, Chasman DI, Willer CJ, Pirruccello J, Johansen CT, Fouchier SW, [plus > 100 additional authors], Rotter JI, Boerwinkle E, Strachan DP, Mooser V, Cupples AL, Sandhu MS, Ridker PM, Rader DJ, van Duijn CM, Peltonen L, Abecasis GR, Boehnke M, Kathiresan S, for the Global Lipids Genetics Consortium. (2010) Biological, clinical and population relevance of 95 loci mapped for serum lipid concentrations. Nature 466(7307):707-13
37. Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, [ plus > 100 additional authors], Florez JC, Frayling TM, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn C, Stefansson K, Altshuler D, Boehnke M, McCarthy MI. (2010) Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nature Genetics 42: 579.589
36. Li Y, Willer C, Sanna S, Abecasis G. (2009) Genotype Imputation. Annu Rev Genomics Hum Genet 10:387-406.
35. Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G, Willer CJ, Herrera BM, Jackson AU, Lim N, Scheet P, Soranzo N, Amin N, Aulchenko YS, Chambers JC, Drong A, Luan J, Lyon HN, Rivadeneira F, Sanna S, Timpson NJ, Zillikens MC, Zhao JH, Almgren P, Bandinelli S, Bennett AJ, Bergman RN, Bonnycastle LL, Bumpstead SJ, Chanock SJ, Cherkas L, Chines P, Coin L, Cooper C, Crawford G, Doering A, Dominiczak A, Doney AS, Ebrahim S, Elliott P, Erdos MR, Estrada K, Ferrucci L, Fischer G, Forouhi NG, Gieger C, Grallert H, Groves CJ, Grundy S, Guiducci C, Hadley D, Hamsten A, Havulinna AS, Hofman A, Holle R, Holloway JW, Illig T, Isomaa B, Jacobs LC, Jameson K, Jousilahti P, Karpe F, Kuusisto J, Laitinen J, Lathrop GM, Lawlor DA, Mangino M, McArdle WL, Meitinger T, Morken MA, Morris AP, Munroe P, Narisu N, Nordstr?m A, Nordstr?m P, Oostra BA, Palmer CN, Payne F, Peden JF, Prokopenko I, Renstr?m F, Ruokonen A, Salomaa V, Sandhu MS, Scott LJ, Scuteri A, Silander K, Song K, Yuan X, Stringham HM, Swift AJ, Tuomi T, Uda M, Vollenweider P, Waeber G, Wallace C, Walters GB, Weedon MN; The Wellcome Trust Case Control Consortium, Witteman JC, Zhang C, Zhang W, Caulfield MJ, Collins FS, Davey Smith G, Day IN, Franks PW, Hattersley AT, Hu FB, Jarvelin MR, Kong A, Kooner JS, Laakso M, Lakatta E, Mooser V, Morris AD, Peltonen L, Samani NJ, Spector TD, Strachan DP, Tanaka T, Tuomilehto J, Uitterlinden AG, van Duijn CM, Wareham NJ, Watkins For The Procardis Consortia H, Waterworth DM, Boehnke M, Deloukas P, Groop L, Hunter DJ, Thorsteinsdottir U, Schlessinger D, Wichmann HE, Frayling TM, Abecasis GR, Hirschhorn JN, Loos RJ, Stefansson K, Mohlke KL, Barroso I, McCarthy For The Giant Consortium MI. (2009) Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution. PLoS Genet 5(6) (early online).
34. Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH, Heath SC, Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F, Farrall M, Tanaka T, Wallace C, Chambers JC, Khaw KT, Nilsson P, van der Harst P, Polidoro S, Grobbee DE, Onland-Moret NC, Bots ML, Wain LV, Elliott KS, Teumer A, Luan J, Lucas G, Kuusisto J, Burton PR, Hadley D, McArdle WL; Wellcome Trust Case Control Consortium, Brown M, Dominiczak A, Newhouse SJ, Samani NJ, Webster J, Zeggini E, Beckmann JS, Bergmann S, Lim N, Song K, Vollenweider P, Waeber G, Waterworth DM, Yuan X, Groop L, Orho-Melander M, Allione A, Di Gregorio A, Guarrera S, Panico S, Ricceri F, Romanazzi V, Sacerdote C, Vineis P, Barroso I, Sandhu MS, Luben RN, Crawford GJ, Jousilahti P, Perola M, Boehnke M, Bonnycastle LL, Collins FS, Jackson AU, Mohlke KL, Stringham HM, Valle TT, Willer CJ, Bergman RN, Morken MA, D?ring A, Gieger C, Illig T, Meitinger T, Org E, Pfeufer A, Wichmann HE, Kathiresan S, Marrugat J, O'Donnell CJ, Schwartz SM, Siscovick DS, Subirana I, Freimer NB, Hartikainen AL, McCarthy MI, O'Reilly PF, Peltonen L, Pouta A, de Jong PE, Snieder H, van Gilst WH, Clarke R, Goel A, Hamsten A, Peden JF, Seedorf U, Syv?nen AC, Tognoni G, Lakatta EG, Sanna S, Scheet P, Schlessinger D, Scuteri A, D?rr M, Ernst F, Felix SB, Homuth G, Lorbeer R, Reffelmann T, Rettig R, V?lker U, Galan P, Gut IG, Hercberg S, Lathrop GM, Zelenika D, Deloukas P, Soranzo N, Williams FM, Zhai G, Salomaa V, Laakso M, Elosua R, Forouhi NG, V?lzke H, Uiterwaal CS, van der Schouw YT, Numans ME, Matullo G, Navis G, Berglund G, Bingham SA, Kooner JS, Connell JM, Bandinelli S, Ferrucci L, Watkins H, Spector TD, Tuomilehto J, Altshuler D, Strachan DP, Laan M, Meneton P, Wareham NJ, Uda M, Jarvelin MR, Mooser V, Melander O, Loos RJ, Elliott P, Abecasis GR, Caulfield M, Munroe PB. (2009) Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet 41:666-676.
33. Willer CJ*, Speliotes EK*, Loos RJ*, Li S*, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L, Randall JC, Roccasecca RM, Sanna S, Scheet P, Weedon MN, Wheeler E, Zhao JH, Jacobs LC, Prokopenko I, Soranzo N, Tanaka T, Timpson NJ, Almgren P, Bennett A, Bergman RN, Bingham SA, Bonnycastle LL, Brown M, Burtt NP, Chines P, Coin L, Collins FS, Connell JM, Cooper C, Smith GD, Dennison EM, Deodhar P, Elliott P, Erdos MR, Estrada K, Evans DM, Gianniny L, Gieger C, Gillson CJ, Guiducci C, Hackett R, Hadley D, Hall AS, Havulinna AS, Hebebrand J, Hofman A, Isomaa B, Jacobs KB, Johnson T, Jousilahti P, Jovanovic Z, Khaw KT, Kraft P, Kuokkanen M, Kuusisto J, Laitinen J, Lakatta EG, Luan J, Luben RN, Mangino M, McArdle WL, Meitinger T, Mulas A, Munroe PB, Narisu N, Ness AR, Northstone K, O'Rahilly S, Purmann C, Rees MG, Ridderstrle M, Ring SM, Rivadeneira F, Ruokonen A, Sandhu MS, Saramies J, Scott LJ, Scuteri A, Silander K, Sims MA, Song K, Stephens J, Stevens S, Stringham HM, Tung YC, Valle TT, Van Duijn CM, Vimaleswaran KS, Vollenweider P, Waeber G, Wallace C, Watanabe RM, Waterworth DM, Watkins N; Wellcome Trust Case Control Consortium, Witteman JC, Zeggini E, Zhai G, Zillikens MC, Altshuler D, Caulfield MJ, Chanock SJ, Farooqi IS, Ferrucci L, Guralnik JM, Hattersley AT, Hu FB, Jarvelin MR, Laakso M, Mooser V, Ong KK, Ouwehand WH, Salomaa V, Samani NJ, Spector TD, Tuomi T, Tuomilehto J, Uda M, Uitterlinden AG, Wareham NJ, Deloukas P, Frayling TM, Groop LC, Hayes RB, Hunter DJ, Mohlke KL, Peltonen L, Schlessinger D, Strachan DP, Wichmann HE, McCarthy MI, Boehnke M, Barroso I, Abecasis GR, Hirschhorn JN; Genetic Investigation of ANthropometric Traits Consortium. (2009) Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 41(1):25-34.
32. Kathiresan S*, Willer CJ*, Peloso G*, Demissie S*, Musunuru K, Schadt E, Kaplan L, Bennett D, Li Y, Tanaka T, Voight BF, Bonnycastle LL, Jackson AU, Crawford G, Surti A, Guiducci C, Burtt N, Parish S, Clarke R, Zelenika D, Kubalanza KA, Morken MA, Scott LJ, Stringham HM, Galan P, Swift AJ, Kuusisto J, Bergman RN, Sundvall J, Laakso M, Ferrucci L, Scheet P, Sanna S, Uda M, Yang Q, Lunetta K, Dupuis J, deBakker P, O'Donnell CJ, Chambers JC, Kooner JS, Hercberg S, Meneton P, Lakatta EG, Scuteri A, Schlessinger D, Tuomilehto J, Collins FS, Groop L, Altshuler D, Collins R, Lathrop M, Melander O, Salomaa V, Peltonen L, Orho-Melander J, Ordovas JM, Boehnke M, Abecasis GR, Mohlke KL, Cupples LA. Common DNA sequence variants at thirty genetic loci contribute to polygenic dyslipidemia. Nat Genet 41(1):25-34.
31. Gaulton KJ, Willer CJ, Li Y, Scott LJ, Conneely KN, Jackson AU, Duren WL, Chines PS, Narisu N, Bonnycastle LL, Luo JJ, Tong M, Sprau AG, Pugh EW, Doheny KF, Valle TT, Abecasis GR, Tuomilehto J, Bergman RN, Collins FS, Boehnke M, Mohlke KL (2008). Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes. Diabetes 57(11):3136-44.
30. Chen WM, Erdos MR, Jackson AU, Saxena R, Sanna S, Silver KD, Timpson NJ, Hansen T, Orr?? M, Grazia Piras M, Bonnycastle LL, Willer CJ, Lyssenko V, Shen H, Kuusisto J, Ebrahim S, Sestu N, Duren WL, Spada MC, Stringham HM, Scott LJ, Olla N, Swift AJ, Najjar S, Mitchell BD, Lawlor DA, Smith GD, Ben-Shlomo Y, Andersen G, Borch-Johnsen K, J??rgensen T, Saramies J, Valle TT, Buchanan TA, Shuldiner AR, Lakatta E, Bergman RN, Uda M, Tuomilehto J, Pedersen O, Cao A, Groop L, Mohlke KL, Laakso M, Schlessinger D, Collins FS, Altshuler D, Abecasis GR, Boehnke M, Scuteri A, Watanabe RM. (2008) Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest. 118(7):2620-2628.
29. Loos RJF, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM, Attwood AP, Beckmann JS, Berndt SI, The Prostate Lung Colorectal and Ovarian (PLCO) Cancer Screening Trial, Bergmann S, Bennett AJ, Bingham SA, Bochud M, Brown M, Cauchi S, Connell JM, Cooper C, Davey Smith G, Day I, Dina C, De S, Dermitzakis ET, Doney ASF, Elliott KS, Elliott P, Evans DM, Farooqi IS, Froguel P, Ghori J, Groves CJ, Gwilliam R, Hadley D, Hall AS, Hattersley AT, Hebebrand J, Heid IM, KORA, Herrera B, Hunt SE, Jarvelin MR, Johnson T, Jolley JM, Karpe F, Keniry A, Khaw KT, Luben RN, Mangino M, Marchini J, McArdle WL, McGinnis R, Meyre D, Munroe PB, Morris AD, Ness AR, Neville MJ, Nica AC, Ong KK, O???Rahilly S, Owen KR, Palmer CNA, Papadakis K, Potter S, Pouta A, Qi L, Nurses' Health Study, Randall JC, Rayner NW, Ring SM, Sandhu MS, Sims MA, Song K, Soranzo N, Speliotes EK, Diabetes Genetics Initiative, Syddall HE, Teichmann SA, Timpson NJ, Tobias JH, Uda M, The SardiNIA Study, Wallace C,Waterworth DM, Weedon MN, The Wellcome Trust Case Control Consortium, Willer CJ, FUSION, Wraight VL, Yuan X, Zeggini E, Hirschhorn JN, Strachan DP, Ouwehand WH, Caulfield MJ, Samani NJ, Frayling TM, Vollenweider P, Waeber G, Mooser V, Deloukas P, McCarthy MI, Wareham NJ, Barroso I. (2008) Association studies involving over 90,000 samples demonstrate that common variants near to MC4R influence fat mass, weight and risk of obesity. Nat Genet 40(6):768-75.
28. Zeggini E, Scott LJ, Saxena R, Voight BF, Marchini JL, Hu T, de Bakker PI, Abecasis GR, Almgren P, Andersen G, Ardlie K, Bostr??m KB, Bergman RN, Bonnycastle LL, Borch-Johnsen K, Burtt NP, Chen H, Chines PS, Daly MJ, Deodhar P, Ding CJ, Doney AS, Duren WL, Elliott KS, Erdos MR, Frayling TM, Freathy RM, Gianniny L, Grallert H, Grarup N, Groves CJ, Guiducci C, Hansen T, Herder C, Hitman GA, Hughes TE, Isomaa B, Jackson AU, J??rgensen T, Kong A, Kubalanza K, Kuruvilla FG, Kuusisto J, Langenberg C, Lango H, Lauritzen T, Li Y, Lindgren CM, Lyssenko V, Marvelle AF, Meisinger C, Midthjell K, Mohlke KL, Morken MA, Morris AD, Narisu N, Nilsson P, Owen KR, Palmer CN, Payne F, Perry JR, Pettersen E, Platou C, Prokopenko I, Qi L, Qin L, Rayner NW, Rees M, Roix JJ, Sandb??k A, Shields B, Sj??gren M, Steinthorsdottir V, Stringham HM, Swift AJ, Thorleifsson G, Thorsteinsdottir U, Timpson NJ, Tuomi T, Tuomilehto J, Walker M, Watanabe RM, Weedon MN, Willer CJ; Wellcome Trust Case Control Consortium, Illig T, Hveem K, Hu FB, Laakso M, Stefansson K, Pedersen O, Wareham NJ, Barroso I, Hattersley AT, Collins FS, Groop L, McCarthy MI, Boehnke M, Altshuler D. (2008) Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 40(5):638-45.
27. Willer CJ*, Sanna S*, Jackson AU, Scuteri A, Bonnycastle LL, Clarke R, Heath SC, Timpson NJ, Najjar SS, Stringham HM, Strait J, Duren WL, Maschio A, Busonero F, Mulas A, Albai G, Swift AJ, Morken MA, Narisu N, Bennett D, Parish S, Shen H, Galan P, Meneton P, Hercberg S, Zelenika D, Chen W-M, Li Y, Scott LJ, Scheet PA, Sundvall J, Watanabe RM, Nagaraja R, Ebrahim S, Lawlor DA, Ben-Shlomo Y, Davey-Smith G, Shuldiner AR, Collins R, Bergman RN, Uda M, Tuomilehto J, Cao A, Collins FS, Lakatta E, Lathrop GM, Boehnke M, Schlessinger D, Mohlke KL, Abecasis GR. (2008) Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 40(2):161-9.
26. Sanna S, Jackson AU, Nagaraja R, Willer CJ, Chen W-M, Bonnycastle LL, Shen H, Timpson N, Lettre G, Usala G, Chines PS, Stringham HM, Dei M, Lai S, Albai, G, Crisponi L, Naitza S, Doheny KF, Pugh EW, Shlomo YB, Ebrahim S, Lawlor DA, Bergman RN, Watanabe RM, Uda M, Tuomilehto J, Coresh J, Hirschhorn JN, Shuldiner AR, Schlessinger D, Collins FS, Davey Smith G, Boerwinkle E, Cao A, Boehnke M, Abecasis GR, Mohlke KL. (2008) Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet 40(2):198-203.
25. Franks PW, Rolandsson O, Debenham SL, Fawcett KA, Payne F, Dina C, Froguel P, Mohlke KL, Willer C, Olsson T, Wareham NJ, Hallmans G, Barroso I, Sandhu MS. (2008) Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations. Diabetologia 51(3):458-63.
24. Dyment DA, Cader MZ, Herrera MB, Ramagopalan SV, Orton SM, Chao M, Willer CJ, Sadovnick AD, Risch N, Ebers GC. (2008) A genome-scan in a single pedigree with a high prevalence of multiple sclerosis. J Neurol Neurosurg Psychiatry 79(2):158-62.
23. Willer CJ, Dyment DA, Cherny S, Ramagopalan SV, Herrera BM, Morrison KM, Sadovnick AD, Risch NJ, Ebers GC. (2007) A genome-wide scan in forty large pedigrees with multiple sclerosis. J Hum Genet. 52(12):955-62.
22. Herrera B, Cader M, Dyment D, Bell J, Deluca G, Willer C, Lincoln M, Ramagopalan S, Chao M, Orton SM, Sadovnick A, Ebers G. (2007) Multiple sclerosis susceptibility and the X chromosome. Mult Scler. 7:856-864.
21. Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, Duren WL, Erdos MR, Stringham HM, Chines P, Jackson AU, Prokunina-Olsson L, Ding C-J, Swift AJ, Narisu N, Hu T, Pruim R, Xiao R, Li X-Y, Conneely KN, Riebow NL, Sprau AG, Tong M, White PP, Hetrick KN, Barnhart MW, Bark CW, Goldstein JL, Watkins L, Xiang F, Saramies J, Buchanan TA, Watanabe RM, Valle TT, Kinnunen L, Abecasis GR, Pugh EW, Doheny KF, Bergman RN, Tuomilehto J, Collins FS, Boehnke M. (2007) A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316(5829):1341-5.
20. Willer CJ, Bonnycastle LL, Conneely KN, Duren WL, Jackson AU, Scott LJ, Narisu N, Chines PS, Skol A, Stringham HM, Petrie J, Erdos MR, Swift AJ, Enloe ST, Sprau AG, Smith E, Tong M, Doheny KF, Pugh EW, Watanabe RM, Buchanan TA, Valle TT, Bergman RN, Tuomilehto J, Mohlke KL, Collins FS, Boehnke M. (2007) Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes. Diabetes 56(1): 256-264.
19. Scott LJ, Bonnycastle LL, Willer CJ, Sprau AG, Jackson AU, Narisu N, Duren WL, Chines PS, Stringham HM, Erdos MR, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Collins FS, Boehnke M. (2006) Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes 55(9): 2649-2653.
18. Bonnycastle LL*, Willer CJ*, Conneely KN, Jackson AU, Burrill CP, Watanabe RM, Chines PS, Narisu N, Scott LJ, Enloe ST, Swift AJ, Duren WL, Stringham HM, Erdos MR, Riebow NL, Buchanan TA, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Boehnke M, Collins FS. (2006) Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns. Diabetes 55(9):2534-2540.
17. Willer CJ, Herrera BM, Morrison KM, Sadovnick AD, Ebers GC; Canadian Collaborative Study on Genetic Susceptibility to Multiple Sclerosis. (2006) Association between microchimerism and multiple sclerosis in Canadian twins. J Neuroimmunol 179(1-2): 145-151.
16. Willer CJ, Scott LJ, Bonnycastle LL, Jackson AU, Chines P, Pruim R, Bark CW, Tsai Y-Y, Pugh EW, Doheny KF, Kinnunen L, Valle TT, Bergman RN, Tuomilehto J, Collins FS, Boehnke M. (2006) Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database. Genetic Epidemiology 30(2):180-190.
15. Willer CJ, Dyment DA, Sadovnick AD, Ebers GC. (2005) Maternal???offspring HLA-DRB1 compatibility in multiple sclerosis. Tissue Antigens 66:44-47.
14. Dyment DA, Herrera BM, Cader MZ, Willer CJ, Lincoln MR, Sadovnick AD, Risch NJ, Ebers GC. (2005). Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance. Hum Mol Genet 14:2019-2026.
13. Willer CJ, Dyment DA, Sadovnick AD, Rothwell PM, Murray TJ, Ebers GC, Canadian Collaborative Study Group. (2005) Timing of birth and risk of multiple sclerosis: population based study. BMJ 330(7483):120.
12. Ebers GC, Sadovnick AD, Dyment DA, Yee IML, Willer CJ, Risch N. (2004) Parent-of-origin effect in multiple sclerosis: observations in half-siblings. Lancet 363: 1773-1774.
11. Dyment DA, Steckley JL, Morrison K, Willer CJ, Cader MZ, DeLuca GC, Sadovnick AD, Risch N, Ebers GC. (2004) TCR beta polymorphisms and multiple sclerosis. Genes Immun 2004 5:337-42.
10. Dyment DA, Sadovnick AD, Willer CJ, Armstrong H, Cader ZM, Wiltshire S, Kalman B, Risch N, Ebers GC. (2004) An extended genome scan in 442 Canadian multiple sclerosis-affected sibships: a report from the Canadian Collaborative Study Group. Hum Mol Genet 13: 1005-1015.
9. Willer CJ, Dyment DA, Risch NJ, Sadovnick AD, Ebers GC and the Canadian Collaborative Study Group. (2003) Twin concordance and sibling recurrence rates in multiple sclerosis. PNAS 100: 12877-12882.
8. Willer CJ, Sadovnick AD, Ebers GC. (2002) Microchimerism in autoimmunity and transplantation: potential relevance to multiple sclerosis. J. Neuroimm 126:126-33.
7. Dyment DA, Cader MZ, Willer CJ, Risch N, Sadovnick AD, Ebers GC. (2002) A multigenerational family with multiple sclerosis. Brain 125: 1-9.
6. Dyment DA, Steckley JL, Willer CJ, Armstrong H, Sadovnick AD, Risch N, Ebers GC. (2002) No evidence to support CTLA-4 as a susceptibility gene in MS families: the Canadian Collaborative Study. J. Neuroimmunol 123(1-2):193-8.
5. Dyment DA, Willer CJ, Scott B, Armstrong H, Ligers A, Hillert J, Sadovnick AD, Risch N, Ebers GC. (2001) Genetic susceptibility to MS: a second stage analysis in Canadian MS families. Neurogenetics 3(3): 145-51.
4. Pericak-Vance MA, Rimmler JB, Saunders AM, Martin ER, Haines JL, Garcia ME, Oksenberg JR, Barcellos LF, Lincoln R, Goodkin DE, Hauser SL, Compston DAS, Sawcer SJ, Clayton D, Jones HB, Walker N, Goodfellow PPN, Bulman D, Sadovnick D, Ebers GC, Dyment D, Willer C, Risch N. (2001) A meta-analysis of genomic screens in multiple sclerosis. Multiple sclerosis 7(1): 3-11.
3. Ligers A, Dyment DA, Willer CJ, Sadovnick AD, Ebers G, Risch N, Hillert J. (2001) Evidence of linkage with HLA-DR in DRB1*15-negative families with multiple sclerosis. Am J Hum Genet 69 (4): 900-3.
2. Willer CJ, Ebers GC. (2000) Susceptibility to multiple sclerosis: interplay between genes and environment. Current Opinion in Neurology 13(3):241-7.
1. Willer B, Button J, Willer C, Good DW. (1999) Performance of administrators, professionals, and paraprofessionals during community-based brain injury rehabilitation training. J Head Trauma Rehab 13(3):82-93.