
Chen Sun
Scientist
Ann Arbor AlgorithmsE-mail: cnsun AT umich DOT edu
Google Scholar
Education
2017.7 - 2023.5 | PhD in Bioinformatics | University of Michigan, Ann Arbor, MI, USA |
2019.9 - 2023.5 | M.A. in Statistics | University of Michigan, Ann Arbor, MI, USA |
2014.9 - 2017.3 | M.S. in Bioinformatics (with honors) | Shanghai Jiao Tong University, Shanghai, China |
2010.9 - 2014.7 | B.S. in Bioinformatics | Shanghai Jiao Tong University, Shanghai, China |
2012.2 - 2014.7 | B.A. in History | Shanghai Jiao Tong University, Shanghai, China |
Experiences
2023.5 - Present | Scientist | Ann Arbor Algorithms, Ann Arbor, MI, USA |
2017.7 - 2023.5 | Research Assistant | University of Michigan, Ann Arbor, MI, USA |
2022.6 - 2022.9 | Applied Scientist Intern | Amazon, Palo Alto, CA, USA |
2012.7 - 2017.3 | Research Assistant | Shanghai Jiao Tong University, Shanghai, China |
2014.3 - 2017.3 | Intern | Shanghai Center for Bioinformation Technology, Shanghai, China |
Research Interests
- AI application in healthcare and biomedicine
- Bioinformatics
- Genetic variation
- Population and comparative genomics
- Genome browser and data visualization
Research Experiences
- Development of Deep Learning Models for Digital Biomarker Discovery (2023-Present)
- Deep learning-based single cell CNV caller development (2022 - 2023)
- Single cell CNV simulator (2021 - 2023)
- Identification of Somatic CNV in Human Neurons with Single-cell sequencing (2019 - 2023)
- Predicting Multiple Myeloma Prognosis (Winter rotation, 2018)
- Simulation of Cancer Progression (Fall rotation, 2017)
- Validation of L1-Hs Insertions using 10X Genomics (Summer rotation, 2017)
- 3000 Rice Genomes Project (Nov. 2013 - Mar. 2017)
- Rice Pan-genome Browser for 3000 Rice Genomes Project (RPAN, Mar. 2015 - Apr. 2016)
- Toolbox for Eukaryotic Pan-genome Analysis (EUPAN, Sept. 2015 - June 2016)
- Shigella Pan-genome Project (Dec. 2015 - June 2016)
- Sensor Based Human Activity Recognition (Apr. 2015 - June 2015)
- Epigenetic Signal Character around TFBS (Oct. 2013 - June 2014)
- Taxonomic Classification of Short Genomic Sequences (Nov. 2013 - Dec. 2013)
- Horizontal Gene Transfer in Human Genome (Summer Intern, 2013)
- Epigenetics within Repeat Region in Mammal Genomes (Summer Intern, 2012)
- Enzymatic Activity of Microorganisms Associated with Sponge (Oct. 2010 - Apr. 2012)
Publications
- Sun, C. et al. "RPAN: Rice Pan-genome Browser for ~3000 Rice Genomes", Nucleic Acids Res., 2017; 45 (2): 597-605. doi: 10.1093/nar/gkw958. [Full Text]
- Hu, Z.#, Sun, C.# et al. "EUPAN enables pan-genome studies of a large number of eukaryotic genomes", Bioinformatics, 2017; 33(15) :2408-2409. doi: 10.1093/bioinformatics/btx170. [Full Text]
- Sun, C. et al. "Prognostic model for multiple myeloma progression integrating gene expression and clinical features", GigaScience, 2019. doi: 10.1093/gigascience/giz153. [Full Text]
- Huang, W. et al. "Widespread of Horizontal Gene Transfer in the Human Genome", BMC Genomics, 2017; 18:274. doi: 10.1186/s12864-017-3649-y. [Full Text]
- Wang, W. et al. "Genomic variation in 3,010 diverse accessions of Asian cultivated rice", Nature, 2018. doi: 10.1038/s41586-018-0063-9. [Full Text]
- Hu, Z. et al., "Novel sequences, structural variations and gene presence variations of Asian cultivated rice", Scientific Data, 2018. doi:10.1038/sdata.2018.79. [Full Text]
- Qiao, Y. et al. "MetaBinG2: a fast and accurate metagenomic sequence classification system for samples with many unknown organisms", Biology Direct, 2018. doi:10.1186/s13062-018-0220-y. [Full Text]
- Yan, F. et al. "Discovery and characterization of the evolution, variation and functions of diversity-generating retroelements using thousands of genomes and metagenomes", BMC Genomics, 2019. doi:10.1186/s12864-019-5951-3. [Full Text]
- Duan, Z. et al. "HUPAN: a pan-genome analysis pipeline for human genomes", Genome Biology, 2018. doi:10.1186/s13059-019-1751-y. [Full Text]
- Sun, C. et al. "Mapping Mosaic Copy Number Variation in Human Neurons", Nature Communications, 2024; Accepted. [Full Text on Biorxiv]
(# co-first author)
Awards
- Pandemic Research Recovery Grant, University of Michigan in 2022
- University of Michigan Rackham Travel Grant in 2018
- Excellent Graduate of Shanghai in 2017
- Graduate Academic Scholarship of SJTU in 2014, 2015 and 2016
- Academic Excellence Scholarship of SJTU in 2012 and 2013
- Excellent Shanghai Undergraduate Innovation Program in 2012
Technical Skills
- Programming Languages:
- Proficient in Python, R, C/C++, Bash, PHP, HTML, CSS, MySQL, Latex
- Exposure to Perl, Matlab, C/C++, JavaScript, Ruby, Pascal, Delphi
Personal Preference
- Reading: Sci-Fi novels, History, Philosophy, etc.
- Travelling: Hiking, Road trip.
- Sports: Basketball, Table tennis, Swimming, Chinese chess.
- Culinary arts: Chinese food.