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Background: In your brain, neurons communicate by transmitter molecules that are released from neurons and transfer messages to other neurons. Thereafter, transmitters or components of the molecule are recycled back into neurons with the help of proteins called neurotransmitter transporters. Two such transporters are the choline transporter (CHT; recycles choline) and the norepinephrine transporter (NET; recycles norepinephrine). There are several known genetic variations of these transporters. There are no diseases or behavioral or cognitive traits associated with these variations, although NET variations may be associated with ADHD. Goals: The first goal of this project is to find participants expressing variations in the CHT and NET. Participants will complete paper and pencil forms & questionnaires and will donate a saliva sample for CHT/NET sequence analysis. Future study opportunities will be available for participation in behavioral and brain imaging experiments to determine whether variations in cognitive performance are associated with variations in these transporter molecules. |
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