I'm a Postdoctoral Research Fellow at the University of Michigan, working with Gonçalo Abecasis, Michael Boehnke and Noah Rosenberg.

I received my B.A. in biology in 1995 from Washington University in St. Louis and then worked for Bob Waterston and LaDeana Hillier at the Genome Sequencing Center. In 2000, I received a M.S. in statistics from The University of Iowa. In June of 2006 at the University of Washington, I completed my Ph.D. in statistics (emphasis in statistical genetics) under the direction of Matthew Stephens. My dissertation was entitled "A Flexible and Computationally Tractable Model for Patterns of Population Genetic Variation".

My current work involves methods for acccurately imputing missing genotypes in population genetic data sets, modelling haplotype variation, mapping rare disease variants, and modelling genotyping errors. I am a member of the Analysis Team of the the 1000 Genomes Project.

Software

Information on fastPHASE (including links for registration and download) may be obtained from the Stephens Lab Software page.

   (fastPHASE documentation is also available here)

Publications

M. Jakobsson*, S. W. Scholz*, P. Scheet*, J Raphael Gibbs, J. M. VanLiere, H. Fung, Z. A. Szpiech, J. H. Degnan, R. Guerreiro, J. M. Bras, J. C. Schymick, D. Hernandez, B. J. Traynor, J. Simon-Sanchez, M Matarin, A. Britton, J. van de Leemput, I. Rafferty, H. M. Cann, J. A. Hardy, N. A. Rosenberg, A. B. Singleton. 2008. Genotype, haplotype, and copy number variation in worldwide human populations. Nature (In press)

C.J. Willer*, S. Sanna*, et al. 2008. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nature Genetics 40: 161-169.

Scheet, P and Stephens, M (2006) A Fast and Flexible Statistical Model for Large-Scale Population Genotype Data: Applications to Inferring Missing Genotypes and Haplotypic Phase. American Journal of Human Genetics 78: 629-644

Matthew Stephens, James S Sloan, P D Robertson, Paul Scheet and Deborah A Nickerson (2006) Automating sequence-based detection and genotyping of SNPs from diploid samples Nature Genetics 38: 375-381

Stephens, M and Scheet, P (2005). Accounting for Decay of Linkage Disequilibrium in Haplotype Inference and Missing-Data Imputation. American Journal Human Genetics, 76:449-462.

Sieh W, Basu S, Fu AQ, Rothstein JH, Scheet PA, Stewart WC, Sung YJ, Thompson EA, Wijsman EM (2005) Comparison of marker types and map assumptions using Markov chain Monte Carlo-b ased linkage analysis of COGA data BMC Genet 6 Suppl 1:S11

Anderson, E and Scheet, P (2001). Improving the Estimation of Bacterial Allele Frequencies. Genetics 158: 1383-1386.

International Human Genome Sequencing Consortium (2001). Initial sequencing and analysis of the human genome. Nature 409:860--921

Dunham, I. et al (1999) The DNA sequence of human chromosome 22 Nature 402:489-495

Contacting me

In Person...
SPH II, 4th floor (4317D)

Electronically...
e-mail:  pscheet (att) umich [] edu

Via paper mail...  (for academic use)
Department of Biostatistics, SPH II
1420 Washington Heights
Ann Arbor, MI 48109-2029